General Information
Revision date
2015-07-06
Product name
IsoFlo
Product Synonyms
Forane; Forene; Isoflurane liquid; 1-chloro-2,2,2-trifluoroethyl difluoromethyl ether; 2-Chloro-2- (difluoromethoxy)-1,1,1-trifluoroethane
Chemical name
Not determined
CAS No.
26675-46-7
Emergency telephone
(24 hours) 1-800-424-9300
Icons in SDS
Company Information
company name
Zoetis Inc
e-mail address of the competent person responsible for the Safety Data Sheet
VMIPSrecords@zoetis.com
GHS Information
Signal word
Warning
Hazard Codes
Hazard statements (CLP)
H315, H319, H336
Hazard statements
Code
Statements
H315
Causes skin irritation
Section 2
SECTION 2: Hazards identification
Appearance: Clear, colorless liquid
2.1 Classification of the substance or mixture
Skin Corrosion/Irritation: Category 2 Serious Eye Damage/Eye Irritation: Category 2A Specific target organ systemic toxicity (single exposure): Category 3
EU Classification
EU Indication of danger: Not determined
Signal word
Warning
Hazard statements
H336 - May cause drowsiness and dizziness H319 - Causes serious eye irritation H315 - Causes skin irritation
Precautionary statements
P261 - Avoid breathing dust/fume/gas/mist/vapors/spray P271 - Use only outdoors or in a well-ventilated area P280 - Wear protective gloves/protective clothing/eye protection/face protection P264 - Wash hands thoroughly after handling P304 + P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing P312 - Call a POISON CENTRE/doctor/physician if you feel unwell P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337 + P313 - If eye irritation persists: Get medical advice/attention P302+ P352 - IF ON SKIN: Wash with plenty of soap and water P332 + P313 - If skin irritation occurs: Get medical advice/attention P362 - Take off contaminated clothing and wash before reuse P403 + P233 - Store in a well-ventilated place. Keep container tightly closed P405 - Store locked up P501 - Dispose of contents/container in accordance with all local and national regulations
2.3 Other hazards
Short Term: Anesthetic drug: may cause central nervous system and cardiovascular system effects . Breathing high vapor concentrations may cause central nervous system (CNS) depression resulting in dizziness, light-headedness, headache, nausea, and loss of coordination. Continued inhalation may result in unconsciousness and death. Causes eye irritation . Signs and symptoms might include redness, swelling, blurred vision or pain. Causes skin irritation. Signs and symptoms might include skin rash, itching, redness or swelling. May be harmful if swallowed. Long Term: may have the potential to produce effects on the developing fetus. Known Clinical Effects: Cardiac arrest, hepatic necrosis, hepatic failure, and hepatitis have occurred with use of isoflurane. Isoflurane can produce coronary vasodilation at the arteriolar level. Cardiovascular sensitivity (characterized by severe hypotension and tachycardia) has occured rarely. In susceptible individuals, potent inhalation anesthetic agents, including isoflurane, may trigger a skeletal muscle hypermetabolic state leading to high oxygen demand and the clinical syndrome known as malignant hyperthermia. The clinical syndrome is signaled by hypercapnia, and may include muscle rigidity, tachycardia, tachypnea, cyanosis, arrhythmias, and/or unstable blood pressure. Some of these nonspecific signs may also appear during light anesthesia: acute hypoxia, hypercapnia, and hypovolemia. Australian Hazard Classification
Hazardous Ingredients
Non-Dangerous Goods (NOHSC): Note: This document has been prepared in accordance with standards for workplace safety, which requires the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warning included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.