ADVOCIN, ADVOCID

Hazard statements (CLP)

H302, H373, H402

Code

Statements

H302

Harmful if swallowed

SECTION 2: Hazards identification

Appearance: Sterile solution in 100 and 250 mL amber-glass, multi-dose vials

2.1 Classification of the substance or mixture

Acute Oral Toxicity: Category 4 Specific target organ systemic toxicity (repeated exposure): Category 2 Acute aquatic toxicity: Category 3

EU Classification

EU Indication of danger: Harmful EU Symbol: Xn R48/22 - Harmful: danger of serious damage to health by prolonged exposure if swallowed.

Signal word

Warning

Hazard statements

H302 - Harmful if swallowed H373 - May cause damage to organs through prolonged or repeated exposure ( cartliage , reproductive system , kidneys , central nervous system , heart ) H402 - Harmful to aquatic life

Precautionary statements

P280 - Wear protective gloves/protective clothing/eye protection/face protection P260 - Do not breathe dust/fume/gas/mist/vapors/spray P264 - Wash hands thoroughly after handling P270 - Do not eat, drink or smoke when using this product P273 - Avoid release to the environment P314 - Get medical attention/advice if you feel unwell P301+ P312 - IF SWALLOWED: Call a POISON CENTRE or doctor/physician if you feel unwell P330 - Rinse mouth P501 - Dispose of contents/container in accordance with all local and national regulations

2.3 Other hazards

Short Term: May cause eye, skin and respiratory tract irritation . Drugs of this class have been associated with rare, but potentially serious cardiac events. These events have not been observed from occupational exposures, however, those with preexisting cardiovascular illnesses may be at increased risk from exposure. There is a risk of photosensitization within a few hours after excessive exposure to quinolones. If excess exposure occurs, avoid direct sunlight and wash skin with soap and water. Long Term: This compound may cause cartilage deterioration in knee joints and adverse reproductive effects (based on animal data). Known Clinical Effects: Individuals sensitive to this material or other materials in its chemical class may develop allergic reactions. The most common adverse reactions associated with the use of quinolones include gastrointestinal distress, such as nausea or diarrhea, and central nervous system (CNS) effects, including insomnia, dizziness, and seizures. Quinolones may effect connective tissue structures. Tendonitis and tendon rupture have occurred as late as several months after quinolone treatment. Australian Hazard Classification

Hazardous Ingredients

Non-Dangerous Goods (NOHSC): Note: This document has been prepared in accordance with standards for workplace safety, which require the inclusion of all known hazards of the product or its ingredients regardless of the potential risk. The precautionary statements and warnings included may not apply in all cases. Your needs may vary depending upon the potential for exposure in your workplace.