General Information
Revision date
2008-03-31
Product name
Hormone Replacement Products
Product Synonyms
Premarin, Premarin Cream, Premarin Intravenous, Premphase, Prempro, Congugated
supplier name
Wyeth
Icons in SDS
Company Information
company name
Wyeth
Section 2
SECTION 2: Hazards identification
OSHA Emergency Overview This contains an active pharmaceutical ingredient that can affect body functions; handle with caution. Appearance Pharmaceutical tablet, Physical State Solid Odor Odorless powder, or cream Potential Physical Hazards Powders and solids are presumed to be combustible.
Potential health effects
Eyes May cause mechanical eye irritation. Skin Not available Inhalation Not available Ingestion The most common effects may include, vaginal bleeding irregularities, change in menstrual flow, breast changes (tenderness, pain, enlargement, secretion, lumps), vaginal secretion, headache, vaginal yeast infections, changes in reproductive organs, skin rash, joint pain, diarrhea, dizziness, fatigue, nausea, vomiting, hair loss, and stomach/abdominal cramps/bloating. Increased risks of endometrial cancer, heart attack, pulmonary emboli, deep vein thrombosis, coronary heart disease, stroke, venous thromboembolism, breast cancer, ovarian cancer, dementia, gallbladder disease, mental depression, colitis, central nervous system effects. May impair fertility. May cause harm to the unborn child. Excreted in breast milk. May cause cancer. Please see Patient Package Insert for further information. Therapeutic Target Organ(s) Reproductive System. Listed by NTP and IARC. Not listed by OSHA.
Environmental effects
See Section 12.
