Reactivator, 1250 Reactivator

SECTION 2: Hazards identification

Emergency Overview Appearance: Liquid WARNING! FLAMMABLE LIQUID AND VAPOR. MAY AFFECT THE CENTRAL NERVOUS SYSTEM CAUSING DIZZINESS, HEADACHE OR NAUSEA. CAUSES EYE IRRITATION. MAY CAUSE SKIN AND RESPITORY TRACT IRRITATION. PROLONGED OR REPEATED CONTACT MAY FRY SKIN AND CAUSE DERMATITUS AND BURNS.

Principle Routes of Exposure

Inhalation, Skin Absorption, Skin Contact, Eye Contact, Ingestion Eye Contact Can cause severe eye irritation. Symptoms include stinging, tearing, redness, and swelling of eyes. Can injure eye tissue. Skin Contact Can cause skin irritation. Symptoms may include redness and burning of skin, and other skin damage. Prolonged or repeated contact may dry the skin. Symptoms may include redness, burning, and drying and cracking of the skin, skin burns, and other skin damage. Ingestion Swallowing small amounts of this material during normal handling is not likely to cause harmful effects. Swallowing large amounts may be harmful. This material can get into the lungs during swallowing or vomiting. This results in lung inflammation and other lung injury. Inhalation Breathing of vapor or mist is possible. Breathing small amounts of this material during normal handling is not likely to cause harmful effects. Breathing large amounts may be harmful. Symptoms are not expected at air concentrations below the recommended exposure limits, if applicable (see Section 8.)

Medical Conditions Generally Aggravated by Exposure

Preexisting disorders of the following organs (or organ systems) may be aggravated by exposure to this material: Skin, Upper respiratory tract, lung (for example, Asthma like conditions), liver, kidney, central nervous system, auditory system,. Exposure to this material may aggravate any preexisting condition sensitive to a decrease in available oxygen, such as chronic lung disease, coronary artery disease or anemias. Individuals with preexisting heart disorders may be more susceptible to arrhythmias (irregular heartbeats) if exposed to high concentrations of this material. Symptoms Signs and symptoms of exposure to this material through breathing, swallowing and/or passage of the material through the skin may include: Metallic taste, stomach and intestinal upset (nausea, vomiting, diarrhea), irritation (nose, throat, airways), runny nose, cough, central nervous system excitation (giddiness, drowsiness, weakness, fatigue, nausea, headache, unconsciousness) and other central nervous system effects, temporary changes in mood and behavior, lowered blood pressure, mild temporary changes in liver, effects on heart rate, respiratory depression (slowing of the breathing rate), blurred vision, lack of coordination, confusion, irregular heartbeat, lung edema (fluid buildup in the lung tissue), kidney damage, coma. Target Organs Exposure to this material (or a component) has been found to cause kidney damage in male rats. The mechanism by which this toxicity occurs is specific to the male rat and the kidney effects are not expected to occur in humans. This material (or a component) shortens the time of onset or worsens the liver and kidney damage induced by other chemicals. This material (or a component) shortens the time of onset or worsens the neurotoxic effects induced by other chemicals. Breathing isopropanol vapors has caused damage to the lining of the middle ear in experimental animals. The relevance of this finding to humans is uncertain. Prolonged intentional toluene abuse may lead to damage to many organ systems having effects on: central and peripheral nervous systems, vision, hearing, liver, kidneys, heart, and blood. Such abuse has been associated with brain damage characterized by disturbances in gait, personality changes and loss of memory. Comparable central nervous system effects have not been shown to result from occupational exposure to toluene. Prolonged intentional toluene abuse may lead to hearing loss progressing to deafness. In addition, while noise is known to cause hearing loss in humans, it has been suggested that workers exposed to organic solvents, including toluene, along with noise may suffer greater hearing loss than would be expected from exposure to noise alone. Overexposure to this material (or its components) has been suggested as a cause of the following effects in laboratory animals: mild, reversible liver effects, anemia, respiratory tract damage (nose, throat, and airways), kidney damage, lung damage, effects on hearing, central nervous system damage. Overexposure to this material (or its components) has been suggested as a cause of the following effects in humans: anemia, effects on hearing, kidney damage. Carcinogenicity Toluene may be harmful to the human fetus based on positive test results with laboratory animals. Case studies show that prolonged intentional abuse of toluene during pregnancy can cause birth defects in humans. This material (or a component) has been shown to cause harm to the fetus in laboratory animal studies. Harm to the fetus occurs only at exposure levels that harm the pregnant animal. The relevance of these findings is uncertain. Reproductive hazard Toluene may be harmful to the human fetus based on positive test results with laboratory animals. Case studies show that prolonged intentional abuse of toluene during pregnancy can cause birth defects in humans. This material (or a component) has been shown to cause harm to the fetus in laboratory animal studies. Harm to the fetus occurs only at exposure levels that harm the pregnant animal. The relevance of these findings to humans is uncertain.