Ferti-lome Triple Action Plus RTU

SECTION 2: Hazards identification

EMERGENCY OVERVIEW This product is a pale yellow solid intended for use in formulating a pesticide to control insects on agricultural crops.

Potential health effects

Pyrethrins) (Piperonyl Butoxide)

Principle Routes of Exposure

Eyes, Skin, Oral, Inhalation Human Effects and Symptoms of Overexposure: None noted Acute Eye Contract: May cause temporary eye irritation. Chronic Eye Contact: Chronic exposure not likely from normal use. Acute Skin Contact: May be irritating to skin. Repeat exposure may cause dermatitis. Chronic Skin Contact: May be irritating to skin. Repeat exposure may cause dermatitis. Acute Ingestion: LD50 > 2 g/kg Chronic Ingestion: None noted. Acute Inhalation: LC50>3 mg/L Chronic Inhalation: None noted. Carcinogenicity: *Marginal increases in benign thyroid, parathyroid, ovary, and liver tumors were observed in rats and in the lungs of mice, following lifetime high dose exposure to pyrethrins. The significance of this observation is questionable and under review. The doses at which 1 tumors were observed for pyrethrins greatly exceeded potential human exposures from labeled uses. Doses at which these effects were observed greatly exceed anticipated human dietary intake. At anticipated dietary exposure levels, it is highly unlikely that this product would result in carcinogenic effects. *Supplier Recommendation Eyes, Skin, Oral, Inhalation Human Effects and Symptoms of Overexposure: None noted Acute Eye Contract: May cause temporary eye irritation. Chronic Eye Contact: Chronic exposure not likely from normal use. Acute Skin Contact: LD50> 2 g/kg Chronic Skin Contact: May be irritating to skin. Repeat exposure may cause dermatitis. Acute Ingestion: LD50 > 4.5 g/kg Chronic Ingestion: None noted. Acute Inhalation: LC50> 5.9 mg/L Chronic Inhalation: None noted. Carcinogenicity: *Marginal increases in benign liver tumors in mice were observed in the following lifetime high does exposure to Piperonyl butoxide. The significance of this observation is questionable and under review. The doses at which tumors were observed greatly exceed potential human exposures from labeled uses. Doses at which these effects were observed greatly exceed anticipated human dietary intake. At anticipated dietary exposure levels, it is highly unlikely that this product would result in carcinogenic effects. MUTAGENICITY: *Piperonyl butoxide was not genotoxic in several tests including the Ames mutagenicity assay, chromosome aberration in Chinese hamster ovary (CHO) cells, CHO/HGPRT assay with S9 activation, and in the unscheduled DNA synthesis (UDS) assay in cultured human liver cells. TERATOLOGY/REPRODUCTIVE EFFECTS: *There were no birth defects or adverse effects on reproductive parameters in rats or rabbits. Piperonyl butoxide is not considered to be teratogenic. *Supplier Recommendation

Medical Conditions Generally Aggravated by Exposure

None noted