are reported or mixture 374 in section 0,75 °C 9

Hazard statements (CLP)

H301, H304, H310, H314, H315, H317, H318, H319, H330, H400, H410

Code

Statements

H301

Toxic if swallowed

SECTION 2: Hazards identification

BY EXPOSURE data, System According controls/personal the criteria information product of IN classification for THE to Annex II to REACH this does EVENT not contain 4,5-7 and OF class

2.2 Label elements

protection FIRE any PBT - Regulation (EU) 2020/878 and to Annex II to UK REACH of chemicals or vPvB in percentage ≥ than Temperature: 0,1%. 25 °C 12.4. Do 8.1. Control parameters Kinematic - Environmental IATA Mobility not DGR: breathe viscosity in International soil combustion Product Air products. Fiche 11. MASS Toxicologique Toxicological OF 5-CHLORO-2-

Transport classification

Association is based Dangerous 20,5 on calculation mm2/s Goods Regulation methods as per Annex I of Temperature CLP, Part 4, unless 40 °C determined otherwise in Safety, health and environmental regulations/legislation specific for the substance or mixture The Solubility Information STOT Section IC50 product Immobilization SINGLE not does available EXPOSURE not contain Concentration substances 50% with endocrine Miscibile disrupting con acqua properties in concentration ≥ 0.1% SECTION Partition Information IMDG Valori limite della Identification Advice International coefficient for not firefighters available qualità dell'aria sul of n-octanol/water Maritime Code for dangerous goods posto the di lavoro substance/mixture and of the company/undertaking not applicable Inhalation Vapour ACUTE Does IMO: not Etanolo Seveso TLV_IT International pressure TOXICITY Category 1000,0 meet of aerosols the classification Directive Maritime can cause ppm 2012/18/EU Organization criteria damage for to this health hazard not class available None The GENERAL Density INDEX Aerosol – frazione inalabile 10,0 mg/m3 Product product and/or Identifier identifier INFORMATION hydrolyzes relative in Annex density to form VI of ethanol CLP CAS no. 64-17-5) 0,848 Ethanol g/cm3 is classified for both physical hazards and health hazards. The rate of hydrolysis Use Relative ATE STOT LC50

Environmental hazards

or Chronic Description Do of not vapours NOEC Acute Tox. 3 of various for Algae first eat, kinds aid drink Aquatic measures and/or Plants or smoke during use. Remove any contaminated clothes and personal protective equipment before entering Acute toxicity, category 3 gases or vapours containing 0,00049 particulate mg/l Skeletonema aerosol sprays, costatum fumes, mists, etc.) combined filters are required The Aminofunctional Delegated Regulation Respiratory Reacts Data product on with substances protection is basic not substances polydimethylsiloxane classified devices as and UE) 2020/217 (XIV Atp. CLP) must hazardous acids be used The pursuant if reaction the technical to takes the provisions measures place with set adopted the forth formation in are EC not Regulation of suitable vapors immediately can form acute mixtures Get toxicity, medical with category air, advice/attention which in the presence of ignition sources cause Hazard apparatus With EC50: ethanol classification 100 in mg/l hydrolysis compliance Static and For test indication with the Daphnia standard part of magna silicone EN 138) Water present For a flea) correct in the 48 substance, h), choice Conclusion of respiratory the following by analogy protection applies: device, Controls see show standard that at EN temperatures INGESTION explosions Aquatic even 529 Chronic Have inside the above empty, subject uncleaned Hazardous drink as containers to much the aquatic water Keep as away possible from sources chronic Get medical of toxicity, ignition advice/attention category and do not smoke Do not Take induce precautions vomiting against unless explicitly ENVIRONMENTAL 150°C, due to oxidative authorised electrostatic H310 by charges a doctor. Cool containers EXPOSURE decomposition, Fatal in danger CONTROLS a small quantity of formaldehyde is released contact with water skin May The produce The emissions generated by manufacturing processes, including those generated by ventilation equipment, should be checked to ensure Merck Index an allergic 10th reaction Edition INHALATION Contains Handling Chemical Safety Packing H330 group Get medical advice/attention Fatal if inhaled. immediately. Remove victim to fresh air, away from the accident scene. If the subject stops compliance breathing, Conditions Persistence H301 administer with and for safe artificial environmental degradability storage, respiration standards Toxic including if swallowed Take any suitable incompatibilities precautions for rescue workers SECTION REACTION INRS

TOXICOLOGICAL INFORMATION

METHYL-2H-ISOTHIAZOL-3-ONE sheet) AND 2-METHYL-2H-ISOTHIAZOL-3-ONE (3:1) not H304 - Patty - Industrial Hygiene and Toxicology applicable May be fatal if swallowed and enters airways. 4.2. Store In Most Data the H314 only absence important substances: - Dangerous in the of original experimental symptoms properties container. and data Causes effects, Store for the severe the both product containers skin acute itself, burns and sealed, health and delayed eye Edition in hazards a damage. well ventilated are evaluated place, according away from to the direct properties sunlight. of Keep - N.I. on Sax labelling REACTION MASS OF 5-CHLORO-2- METHYL-2H-ISOTHIAZOL-3-ONE the substances containers it away pursuant to EC Regulation

Contains

Aminofunctional - IFA GESTIS 9. website (3:1) H317 any incompatible using the criteria Physical polydimethylsiloxane: materials, specified and chemical properties May see in cause section the applicable an 10 allergic for details. regulation skin reaction. for classification. 14.5. Specific Solubility in water It is Environmental H400 therefore information necessary on symptoms to take Very into and account toxic effects to the aquatic caused concentration life. by the product > 10000 mg/l of the are individual unknown. hazardous substances indicated in section 3, to evaluate the Skin - ECHA NOT rapidly degradable contact: our direct REACTION MASS OF users 5-CHLORO-2- must, under METHYL-2H-ISOTHIAZOL-3-ONE their own responsibility, comply with AND 14.7. Initial Information - ATE: (Test and safety Maritime system: laws mutation boiling Acute on Toxicity transport point likely routes and regulations. Estimate assay (in vitro) in bulk of exposure according to IMO instruments The producer cells, relieved Method: not available from any OECD 12.3. Bioaccumulative potential liability 471, arising Source: from analysis improper report) uses. / bacterial is 2-METHYL-2H-ISOTHIAZOL-3-ONE (3:1) Flammability - CAS: Chemical Abstract Service Number SUITABLE Provide appointed EXTINGUISHING staff with adequate EQUIPMENT how to use not available chemical products. May produce training an on allergic reaction. Lower Information - CE50: explosive The CARCINOGENICITY extinguishing equipment should be of the conventional kind: carbon dioxide, foam, powder and water spray. Effective not available relevant limit concentration (required to induce a 0,6 50% effect) % (v/v) Upper - CE: Identifier UNSUITABLE CALCULATION EXTINGUISHING explosive in limit METHODS FOR EQUIPMENT ESIS (European archive of existing not substances) available REACTION MASS OF 5-CHLORO-2- METHYL-2H-ISOTHIAZOL-3-ONE AND 2-METHYL-2H-ISOTHIAZOL-3-ONE (3:1) Flash Delayed - CLP: point Regulation and immediate Identification x = Conc. %

Hazard pictograms

website Does not cause skin sensitization. -- Minimum toxicological (Species: - Database Guinea H410 temperature of SDS pig, models effects of during Test system: exposure for chemicals

Storage

Very to the and Maximization toxic product. - Ministry Test, transport: to aquatic 1 life °C with long lasting effects. of Health Method: and OECD ISS (Istituto 406, Source: Superiore Conclusion di Sanità) by - analogy) Italy 4.3. 9.1. Maximum Data on substances: not Indication Information EUH066 applicable temperature of on any basic immediate during physical medical Repeated and and chemical attention transport: exposure properties and 35°C may special cause skin treatment dryness needed or cracking.

Signal word

Aminofunctional polydimethylsiloxane: -- 11.1. GERM Biodegradability: Information EUH071 CELL MUTAGENICITY on hazard classes Corrosive as defined to the in respiratory Regulation

Further information

liquid Does The information Hydrolysis products (Ethanol): not statements: meet the contained

2.1 Classification of the substance or mixture

Association is based Dangerous > 20,5 on calculation mm2/s Goods Regulation methods as per Annex I of Temperature: CLP, Part 4, unless 40 °C determined otherwise in 15.1. Safety, health and environmental regulations/legislation specific for the substance or mixture The Solubility Information STOT - Section IC50: product - Immobilization SINGLE 12. not does available EXPOSURE not contain Concentration substances 50% with endocrine Miscibile disrupting con acqua properties in concentration ≥ 0.1%. 5.3. SECTION Partition Information - IMDG: Valori limite della Identification Advice International coefficient: for not 1. firefighters available qualità dell'aria sul of n-octanol/water Maritime Code for dangerous goods posto the di lavoro: substance/mixture and of the company/undertaking not applicable Inhalation Vapour ACUTE Does - IMO: not Etanolo Seveso TLV_IT International pressure TOXICITY Category 1000,0 meet of aerosols the classification - Directive Maritime can cause ppm 2012/18/EU: Organization criteria damage for to this health. hazard not class available None 1.1. The GENERAL Density - INDEX: Aerosol – frazione inalabile 10,0 mg/m3 Product product and/or Identifier identifier INFORMATION hydrolyzes relative in Annex density to form VI of ethanol CLP (CAS no. 64-17-5). 0,848 Ethanol g/cm3 is classified for both physical hazards and health hazards. The rate of 12.5. hydrolysis Use Relative ATE STOT - LC50: Restrictions relating to the product or contained substances pursuant to Annex XVII to EC Regulation 1907/2006 Results jets (Inhalation) - REPEATED Lethal vapour of and water of PBT Concentration therefore density of to the and cool EXPOSURE mixture: vPvB also the containers 50% the assessment relevance to prevent for the product hazard not available of decomposition Not the product classified depends and (no the significant development strongly component) on the of substances specific conditions. potentially hazardous for Code: health. Particle ATE - LD50: (Oral) Always Lethal characteristics of the dose wear mixture: 50% full fire prevention gear. Collect TPZT extinguishing not applicable Not classified water to prevent (no significant it from component) draining into the sewer system. Dispose of Regulatory Contained references: substance Product contaminated ATE Does On - OEL: the (Dermal) not Occupational basis name meet of water of the available the classification used mixture: Exposure data, for extinction Level the criteria product and for this does the hazard remains not contain TRIPLEZERO class of the any Not fire PBT classified according T or vPvB (no to in applicable significant percentage component) regulations. ≥ than 0,1%. SECTION 3. Composition/information on ingredients Point 75 REACTION MASS OF 5-CHLORO-2- METHYL-2H-ISOTHIAZOL-3-ONE AND SPECIAL - PBT: Persistent DEU PROTECTIVE bioaccumulative Deutschland EQUIPMENT and toxic FOR as FIRE-FIGHTERS Technischen 2-METHYL-2H-ISOTHIAZOL-3-ONE REACH Regulation Regeln für Gefahrstoffe (3:1) (TRGS 900) - Liste der Arbeitsplatzgrenzwerte und 1.2. 9.2. 12.6. Normal 3.2. Mixtures ASPIRATION - PEC: Relevant Other Endocrine Predicted fire information identified fighting HAZARD disrupting environmental clothing uses properties of i.e. the fire Concentration substance kit (BS EN or Kurzzeitwerte. MAK- und BAT-Werte-Liste 2020, Ständige Senatskommission zur Prüfung 469), mixture gloves and (BS uses EN 659) advised and boots against (HO specification A29 and A30) in combination with self-contained - PEL: Predicted Regulation (EU) 2019/1148 - on the marketing REACTION open exposure circuit MASS positive level OF 5-CHLORO-2- pressure compressed gesundheitsschädlicher METHYL-2H-ISOTHIAZOL-3-ONE and use of explosives Arbeitsstoffe, air breathing apparatus (BS precursors Mitteilung 56 AND EN 2-METHYL-2H-ISOTHIAZOL-3-ONE 137). (3:1) Intended Does Based - PNEC: not on LD50 Predicted use meet the (Dermal): available the classification no effect data, concentration the criteria product for does this not hazard contain Hydrophobic class substances 87,12 Viscosity: mg/kg cream listed > 20,5 Rabbit for in mm2/s construction the main European lists of potential or suspected endocrine Contains: not applicable 9.2.1. disruptors - REACH: Information LD50 REACTION MASS OF 5-CHLORO-2- METHYL-2H-ISOTHIAZOL-3-ONE AND 2-METHYL-2H-ISOTHIAZOL-3-ONE with Regulation (Oral): environmental with (EC) regard 1907/2006 effects to physical under hazard evaluation. classes 457 mg/kg Rat 1.3. SECTION 11.2. - RID: Details Information Regulation LC50 of 6. the Accidental (Inhalation on supplier concerning other mists/powders): hazards of the release the safety international data measures sheet transport of dangerous 0,171 mg/l/4h goods Rat by train Identification Substances in Candidate (3:1) List (Art. 59 x REACH) = Conc. % Classification (EC) 1272/2008 (CLP) 12.7. Information 6.1. Threshold - TLV: On Personal Other the basis Limit Threshold adverse precautions, not available of available Limit Value data, effects Value protective the product equipment does not and contain emergency any SVHC procedures in percentage ≥ than 0,1%. Name Assessment: Based - TLV CEILING: on the available Concentration data, the that product should does not be not exceeded contain VOLTECO substances during S.p.A any listed time of in occupational the main European exposure. lists of potential or suspected endocrine Mixture Type of aliphatic Country hydrocarbons TWA/8h STEL/15min Remarks / Observations Full 9.2.2. Respirable disruptors Information - TWA: address Other Time-weighted with aerosols not safety human available characteristics containing health average effects aminofunctional exposure under limit evaluation. polysiloxanes via delle may industrie cause 47 harmful effects on the lungs if inhaled in animal testing. Given the INDEX Block Substances the leakage subject if there to authorisation is no hazard. mg/m3 (Annex 40 ≤ x < XIV 50 ppm REACH) Asp. mg/m3 Tox. 1 ppm H304, EUH066 District many Data - TWA on possible STEL: and substances: Country Short-term influencing exposure factors (e.g. limit amino function, 31050 degree of substitution, Ponzano Veneto viscosity, composition) it is (TV) not possible to estimate the EC Wear None MAK suitable protective 927-676-8 DEU equipment 0,2 (including personal protective 0,4 equipment referred to INHAL under Section 8 of the safety data sheet) to prevent Sustained toxicological Aliphatic - VOC: Volatile CAS any contamination of skin, eyes and personal clothing. These indications apply for both processing staff and those involved in emergency and combustion effects naphthenic organic on the Compounds hydrocarbons: lungs for untested products > 110°C of this (ISO type. 9038) Italia In these cases, the inhalation of respirable aerosols must be prevented by SECTION 13. Disposal considerations Explosion means According - vPvB: of Very appropriate limits to Persistent the literature, technical and aliphatic very measures. Bioaccumulative hydrocarbons as have for Tel. Ethanol a REACH slightly released: Regulation irritating 04229663 3,5-15% effect Vol. on the epidermis and mucous membranes. Degreases the REACH procedures. Legend: Substances Reg. subject 01-2119456377-30 to exportation reporting pursuant to Regulation (EU) 649/2012: e-mail Acute skin. - WGK: Narcotic. Toxicity address Water Estimate In hazard of case the competent classes of (ATE): direct (German). action person on lung tissues (e.g. by aspiration) it can cause pneumonia. 13.1. Aliphatic (C) None Waste = CEILING and treatment naphthalene ; INHAL methods = Inhalable hydrocarbons Fraction ; RESP = Respirable Fraction ; THORA = Thoracic Fraction. responsible ATEmix Hydrolysis (Oral): products for > the 2000 Safety (Ethanol): mg/kg Data Sheet volteco@volteco.it 6.2. INDEX SECTION 10. Stability and reactivity Environmental 649-327-00-6 precautions 10 ≤ x < 20 Asp. Tox. 1 H304, EUH066 8.2. EC Data Ethanol on substances: Reuse, Substances Exposure when controls (64-17-5) is absorbed well and rapidly with all routes of exposure. Ethanol can cause irritation of the eyes and mucous membranes as subject possible. 265-150-3 to the Neat Rotterdam product residues Convention: should be considered special non-hazardous waste. 1.4. Aminofunctional 10.1. CAS well GENERAL The Disposal None Emergency Reactivity as functional product must must be 64742-48-9 BIBLIOGRAPHY telephone polydimethylsiloxane: alterations number performed not penetrate of the central nervous system, nausea and dizziness. Chronic exposure to large quantities of ethanol can cause through into the an sewer authorised system waste or come management into contact firm, with in compliance surface water with or national ground water. and local regulations. Oral damage 1. Regulation REACH As CONTAMINATED the use Reg. of adequate LD50 to > the 2000 (EC) liver mg/kg 01-2119456810-40 PACKAGING 1907/2006 and central (REACH) technical equipment must always take priority over personal protective equipment, make sure that the workplace is nervous system. of the European Parliament For Species: 2. Regulation urgent Rat, inquiries (EC) Source: 1272/2008 refer Conclusion to (CLP) by analogy of the European +39 Parliament 06 68593726 (CAV "Osp. Pediatrico Bambino Gesù" Dip. Emergenza e 6.3. REACTION well There Contaminated Substances Methods aired are through no and MASS subject particular packaging material effective OF to the risks 5-CHLORO-2- for must Stockholm local of containment reaction be aspiration. recovered Convention: METHYL-2H-ISOTHIAZOL-3-ONE with and other or disposed cleaning substances of up in in compliance normal conditions with AND national 2-METHYL-2H-ISOTHIAZOL-3-ONE of use. waste management regulations. (3:1) 3. Regulation (EU) 2020/878 (II Annex of REACH Regulation) INDEX HAND None PROTECTION 613-167-00-5 0 ≤ x < 0,0015 Accettazione DEA - Roma - 00165) Acute Tox. 2 H310, Acute Tox. 2 H330, Acute Tox. 3 H301, Skin Corr. 1C SECTION 12. Ecological information SKIN 4. Regulation CORROSION (EC) 790/2009 / IRRITATION (I Atp. CLP) of the European +39 800183459 Parliament (Az. Osp. Univ. Foggia - Foggia - 71222) 10.2. Collect Protect Chemical the hands leaked stability with product category into III work a suitable gloves. container. Evaluate H314, the compatibility SECTION Eye Dam. 1 of H318, 5. Regulation 14. remainder The Use Healthcare following this product with controls the container (EU) Transport should inert according 286/2011 (II Atp. information Skin Sens. absorbent be considered to be 1A used, to good material. H317, by Aquatic CLP) of the European working when choosing checking Acute practices. work Avoid section 1 H400 +39 081 glove Aquatic Parliament 10. Absorb littering. 7472870 (Az. Osp. "A. Cardarelli" - Napoli - 80131) material Inform M=100, the Chronic (see the standard 1 competent H410 EN M=100, 374): authorities, EUH071, compatibility, should Classification degradation, the product note reach failure according waterways time and to or Repeated 6. Regulation Make permeability. The contaminate Information product sure the exposure not is soil leakage (EU) 618/2012 stable available or vegetation. may cause in site normal is well (III skin conditions Atp. dryness aired. Contaminated CLP) of or the cracking. of use and storage. European +39 06 Parliament material Annex 49978000 (CAV Policlinico "Umberto I" - Roma - 161) should VI to be the disposed CLP Regulation: of in compliance B with the provisions set forth in point 13. The product is not dangerous under current provisions +39 of 06 7. Regulation (EU) 487/2013 (IV Atp. CLP) of the European Parliament the 3054343 Code of (CAV International Policlinico Carriage "A. Gemelli" of Dangerous - Roma Goods - 168) by Road (ADR) and by Rail EC The work gloves' resistance to chemical agents should be checked Skin Corr. before 1C use, H314: the International as it ≥ can 0,6%, be Skin (RID), of the International Maritime Dangerous Goods +39 Code 055 (IMDG), Data 8. Regulation unpredictable. Air Transport on substances: Irrit. 2 H315: (EU) 944/2013 (V Atp. CLP) of the European Parliament The ≥ gloves' Association 0,06%, wear Skin time Sens. depends regulations. 1A H317: on ≥ 7947819 and (Az. of Osp. "Careggi" U.O. Tossicologia Medica (IATA) - Firenze - 50134) 6.4. 10.3. 12.1. 15.2. the Reference Possibility Toxicity Chemical duration and to safety of other type hazardous assessment of sections use. reactions 0,0015%, Eye Dam. 1 H318: ≥ 0,6%, Eye Irrit. 2 H319: ≥ 0,06% Aminofunctional 9. Regulation (EU) polydimethylsiloxane: 605/2014 (VI Atp. CLP) of the European +39 0382 Parliament 24444 (CAV Centro Nazionale di Informazione Tossicologica - Pavia - 14.1. UN number or ID number CAS SKIN PROTECTION 55965-84-9 STA Oral: 100 mg/kg, LD50 Dermal: 87,12 mg/kg, LC50 Inhalation No 10. skin Any Wear No A chemical Regulation hazardous information category irritation (EU) 2015/1221 (VII Atp. CLP) of the European safety reactions I on professional assessment personal are foreseeable protection long-sleeved has not and been in normal overalls disposal performed conditions and is given 27100) for safety the in mists/powders: of footwear Parliament preparation/for sections use and 8 (see storage. and Regulation 13. the 0,171 substances mg/l/4h 2016/425 indicated and standard in section EN 3. ISO 20344). Wash body (Species: 11. Regulation with REACTION soap and MASS Rabbit, (EU) Source: water OF 2016/918 after 5-CHLORO-2- removing protective Conclusion (VIII Atp. by CLP) METHYL-2H-ISOTHIAZOL-3-ONE analogy) of the European clothing. +39 02 66101029 Parliament (Osp. Niguarda Ca' Granda - Milano - 20162) AND 2-METHYL-2H-ISOTHIAZOL-3-ONE (3:1) not applicable 12. Regulation (EU) 2016/1179 (IX Atp. CLP) +39 800883300 (Azienda Ospedaliera Papa Giovanni XXII - Bergamo - 24127) 10.4. The EYE LC50 Conditions full PROTECTION - for wording Fish to of avoid hazard (H) phrases is given in section 16 0,19 of mg/l/96h the sheet. Oncorhynchus mykiss SECTION SERIOUS 13. Regulation Wear EC50 airtight - for Crustacea EYE 7. 16. (EU) protective goggles (see standard EN 166). Handling DAMAGE Other 2017/776 / information IRRITATION and (X Atp. storage CLP) 0,16 mg/l/48h Daphnia magna 14. Regulation (EU) 2018/669 (XI Atp. CLP) RESPIRATORY None EC50 in - for particular. Algae PROTECTION / Aquatic However Plants the usual precautions used for 0,0052 7.1. 14.2. Text SECTION Precautions UN of proper hazard shipping 2. Hazards chemical (H) for indications safe handling mg/l/72h products

2.3 Other hazards

On the basis of available data, the product does not contain any PBT or vPvB in percentage ≥ than 0,1%. The product does not contain substances with endocrine disrupting properties in concentration ≥ 0.1%. Inhalation of aerosols can cause damage to health. The product hydrolyzes to form ethanol (CAS no. 64-17-5). Ethanol is classified for both physical hazards and health hazards. The rate of hydrolysis and therefore also the relevance for the hazard of the product depends strongly on the specific conditions. 3.2. Mixtures