KARBA 50 DP

SECTION 2: Hazards identification

and confusion. In non-fatal cases, the illness generally lasts less than 24 hours. Toxicity class: WHO II, EPA I Chronic exposure: ADI: 0.01 mg/kg b.w Prolonged or repeated exposure may cause effects as NOEL: 200 mg/kg (rats) - 2 year described in acute exposure. ACGIH: 5 mg/m3 Carbaryl First aid: 10 mg/m3 Nuisance dust Remove from exposure area to fresh air immediately. If STEL: 15 mins 10 mg/m3 breathing has stopped, give mechanical artificial TWA: 8 hours 5 mg/m3 respiration (not direct mouth-to-mouth). Maintain airway Main Hazard: Toxic to fish and bees. and blood pressure and administer oxygen if available. Keep affected person warm and at rest. Treat symptomatically and supportively. Qualified personnel should perform administration of oxygen. Get medical head below hips to prevent aspiration). If consciousness attention immediately. level declines or vomiting has not occurred in 15 minutes Skin contact: empty stomach by gastric lavage with the aid of cuffed Acute exposure: endotracheal tube using isotonic saline or 5 % sodium Karba 50 DP may cause irritation. Localised sweating bicarbonate follow with activated charcoal. Establish and and fasciculation’s may occur at the site of contact. If maintain airway. Treat respiratory difficulty with artificial sufficient amounts are absorbed through the skin, other respiration and oxygen. effects of cholinesterase inhibition may occur as described Do not give morphine, aminophylline, phenothiazines, in acute inhalation. Symptoms may be delayed for 2-3 reserpine, furosemide, or ethacrynic acid. Drugs like hours, usually no more than 8 hours. 2 PAM are not effective in poisoning with Carbaryl. Chronic exposure: AND SHOULD NOT BE USED. Repeated or prolonged exposure may cause effects as Treat symptomatically and supportively. Qualified medical described in acute exposure. personnel must perform administration of oxygen and First aid: gastric lavage. Get medical attention immediately. Remove contaminated clothing immediately. Wash Advice to physician: contaminated areas with soap and water followed by Antidote: alcohol. Emergency personnel should wear gloves and The following antidote has been recommended: Atropine. avoid contamination. Treat respiratory difficulty with However, the decision as to whether the severity of mechanical artificial respiration. Get medical attention poisoning requires administration of any antidote and immediately. actual dose required should be made by qualified medical Eye contact: personnel. Acute exposure: For cholinesterase inhibitors: Establish clear airway and Direct contact may cause pain, hyperaemia, lacrimation, tissue oxygenation by aspiration of secretions, and if twitching of the eyelids, miosis, and ciliary muscle spasm necessary, by assisted pulmonary ventilation with oxygen. with loss of accommodation, blurred or dimmed vision and Improve tissue oxygenation as much as possible before browache. Sometimes mydriasis may occur instead of administrating atropine to minimise the risk of ventricular miosis. With sufficient exposure, other symptoms of fibrillation. Administer atropine sulphate intravenously, or cholinesterase inhibition may occur as described in acute intramuscularly if iv injection is not possible. In moderately inhalation. severe poisoning administer atropine sulphate, 0.4-2.0 mg Chronic exposure: repeated every 15 minutes, until atropinization is achieved Prolonged exposure may cause effects as described in (tachycardia, flushing, dry mouth, mydriasis). Maintain acute exposure. Some compounds have caused toxic atropinization by repeated doses for 2-12 hours, or longer, effects on the crystalline lens, conjunctival thickening and depending on the severity of poisoning. The appearance obstruction of nasolacrimal canals when used as miotic of rales in the lung bases, miosis, salivation, nausea, eye drops. bradycardia, are all indications of inadequate First aid: atropinization. Severely poisoned individuals may exhibit Irrigate eyes with water or saline solution. If symptoms of remarkable tolerance to atropine. Two or more times the poisoning occur, treat respiratory difficulty with mechanical dosages suggested above may be needed. Persons not artificial respiration and oxygen. Observe patient for at poisoned or only slightly poisoned, however, may develop least 24-36 hours. Get medical attention immediately. signs of atropine toxicity from such large dosages: fever, Qualified medical personnel should administer oxygen. muscle fibrillations, and delirium are main signs of atropine Ingestion: toxicity. If these signs appear while the patient is fully Acute exposure: atropinized, atropine administration should be When ingested, the first effects may be nausea, vomiting, discontinued, at least temporarily. Observe treated patients anorexia, abdominal cramps, and diarrhoea. With closely at least 24 hours to ensure that symptoms absorption from the gastrointestinal tract, the other effects (possibly pulmonary oedema) do not recur as of cholinesterase inhibition as described in acute inhalation atropinization wears off. In very severe poisonings, may occur. Symptoms may begin within minutes or be metabolic disposition of toxicant may require several hours delayed several hours. or days during which atropinization must be maintained. Chronic exposure: Markedly lower levels of urinary metabolites indicate that Repeated ingestion may cause effects as described in atropine dosage can be tapered off. As dosage is reduced, acute exposure. check the lung bases frequently for rales. If rales are heard First aid: or other symptoms return, re-establish atropinization If person is alert and respiration is not depressed, give promptly. syrup of Ipecac followed by water (if vomiting occurs, keep 5. FIRE FIGHTING MEASURES inhalation of dust and vapour. Use with adequate ventilation. Wash hands before eating, drinking, chewing Fire and explosion hazard: Slight fire hazard when gum, smoking, or using the toilet. Remove clothing exposed to heat or flame. Dust-air mixtures may ignite or immediately if this product gets inside. Then wash skin explode. thoroughly using a non-abrasive soap and put on clean Extinguishing agents: Extinguish small fires with carbon clothing. Do not apply directly to areas where surface dioxide, dry powder, Halon, water spray, or alcohol- water is present, or to intertidal areas below the mean high resistant foam. Water spray can be used for cooling of water mark. Water used to clean equipment must be unaffected stock, but avoid water coming in contact with disposed of correctly to avoid contamination. the product. Contain water used for fire fighting for later Storage: The product must be kept under lock and key. disposal Keep out of reach of unauthorised persons, children and Firefighting: Move containers from fire area if possible. animals. Store in its original labelled container in shaded, Fight fire from maximum distance. Stay away from storage well-ventilated area, away from heat, sparks and other tank ends. Contain fire control water for later disposal. Do sources of ignition. Not to be stored next to foodstuffs and not scatter material, extinguish only if flow can be stopped. water supplies. Local regulations should be complied with. Use flooding amounts of water as a fog as solid streams may be ineffective. Cool containers with flooding amounts 8. EXPOSURE CONTROL / PERSONAL PROTECTION of water as far a distance as possible. Use water spray to absorb toxic vapours. Avoid breathing toxic vapours. Occupational exposure limits: Keep upwind. Consider evacuation of downwind area if Carbaryl Recommended Exposure Limit 10 Hr Time- material is leaking. Weighted Average: 5 mg/cu m. Special Hazards: Fire may produce irritating or Talc: poisonous vapours (carbon monoxide and nitrogen Recommended Exposure Limit: 10 Hr Time Weighted oxides), mists or other products of combustion. Average: 2 mg/cu m (resp). Containing no asbestos and Personal protective equipment: Carbaryl dust may be less than 1% quartz. transported in the smoke from a fire. Fire fighters and Engineering control measures: It is essential to provide others that may be exposed should wear full protective adequate ventilation. The measures appropriate for a clothing and self-contained breathing apparatus. particular worksite depend on how this material is used and on the extent of exposure. Ensure that control