MB593C

SECTION 2: Hazards identification

Principle Routes of Exposure

Dermal contact, Inhalation, Ingestion, Eye contact Short-Term Exposure (Acute) Toluene is irritating to the eyes and the respiratory tract. The substance may cause effects on the central nervous system. If this liquid is swallowed, aspiration into the lungs may result in chemical pneumonitis. Exposure at high levels may result in cardiac dysrhythmia and unconsciousness. (ICSC: 0078) Exposure to petroleum distillates and/or extracts may cause upper respiratory tract irritation. Resorcinol is irritating to the eyes, the skin and the respiratory tract. The substance may cause effects on the blood, resulting in formation of methaemoglobin. The effects may be delayed. Medical observation is indicated. (ICSC# 1033) Sulfur irritates the eyes, the skin and the respiratory tract. Inhalation of powder of this substance may cause inflammation of the nose and the respiratory track. (ICSC: 1166) Short-term inhalation of zinc oxide may result in metal fume fever. The earliest symptoms of metal fume fever are a metallic taste in the mouth accompanied by dryness and irritation of the throat. Flu-like symptoms, chills, fever, profuse sweating, headache, and weakness follow. The symptoms usually occur within several hours after the exposure and persist for 24 to 48 hours. (EPA - Toxicological Review of Zinc and Compounds - 07/2005) Exposure to ethyl alcohol may cause upper respiratory tract irritation. Long-Term Exposure (Chronic) Toluene defats the skin. The substance may have effects on the central nervous system. Exposure to the substance may enhance hearing damage caused by exposure to noise. Animal tests show that this substance possibly causes toxicity to human reproduction or development. (ICSC: 0078) REACH has classified "extracts (petroleum), heavy paraffinic distillate solvent" as presumed human carcinogens (category 1B). Classification " carc. 1B " is largely based on animal evidence. Lungs may be affected by repeated or prolonged exposure to carbon black (ICSC: 0471). IARC has classified carbon black as Group 2B, possibly carcinogenic to humans. This IARC classification is based on sufficient evidence of carcinogenicity in experimental animals, but inadequate evidence in humans. From experiments involving repeated applications of petroleum-derivated base oils and formulated products to the skin of mice, there is sufficient evidence that mineral oils are carcinogenic to humans or present a carcinogenic risk to humans.(IARC Vol. 33) According to GHS, "naphta (petroleum), hydrotreated light" may cause cancer (Carc.1B).It may be fatal if swallowed and enters airways (Asp. Tox. 1) and may cause genetic defects (Muta. 1B). In rare cases, repeated or prolonged contact with resorcinol may cause skin sensitization. (ICSC: 1033) Repeated or prolonged contact to sulfur with skin may cause dermatitis. The substance may have effects on the respiratory tract, resulting in chronic bronchitis (ICSC: 1166). Sulfur is classified as skin irritant (cat. 2) under GHS. Lead and lead compounds are listed by NTP (USA National Toxicology Program) as "reasonably anticipated to be human carcinogens". This is based on limited evidence from studies in humans and sufficient evidence from studies in experimental animals. Carcinogenicity