Pyridine

Hazard statements (CLP)

H225, H302+H312+H332, H315, H319

Code

Statements

H225

Highly Flammable liquid and vapour

EC Classification

WHMIS (Canada) Transportation 2 3 0

2.1 Classification of the substance or mixture

According to Regulation (EC) No 1272/2008) Serious Eye Damage/Eye Irritation Category 2 Skin Corrosion/Irritation Category 2 Acute Toxicity Inhalation Dust / MistCategory 4 Acute Toxicity Dermal Category 4 Acute Toxicity Oral Category 4 Flammable Liquids Category 2

Signal word

Danger Hazard Precautions: H319 - Causes serious eye irritation. H315 - Causes skin irritation. H302+H312+H332 - Harmful if swallowed, in contact with skin or if inhaled. H225 - Highly flammable liquid and vapour.

Prevention

Precautions P271 - Use only outdoors or in a well-ventilated area. P261 - Avoid breathing dust/fume/gas/mist/vapours/spray. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. P280 - Wear protective gloves/protective clothing/eye protection/face protection. P243 - Take precautionary measures against static discharge. P242 - Use only non-sparking tools. P241 - Use explosion-proof electrical/ventilating/lighting/telecommunication/computer/ equipment. P240 - Ground/bond container and receiving equipment. P233 - Keep container tightly closed. P210 - Keep away from heat/sparks/open flames/hot surfaces. – No smoking. First Aid Precautions: P337+P313 - If eye irritation persists: Get medical advice/attention. P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P362 - Take off contaminated clothing and wash before reuse. P332+P313 - If skin irritation occurs: Get medical advice/attention. P321 - Specific treatment (see supplemental information on this label). P304+P340 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P363 - Wash contaminated clothing before reuse. P322 - Specific measures (see supplemental information on this label). P312 - Call a POISON CENTER or doctor/physician if you feel unwell. P302+P352 - IF ON SKIN: Wash with plenty of soap and water. P330 - Rinse mouth. P301+P312 - IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P370+P378 - In case of fire: Use carbon dioxide/dry chemical/soda ash for extinction. P303+P361+P353 - IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.

Storage

Precautions P403+P235 - Store in a well-ventilated place. Keep cool.

Disposal

Precautions P501 - Dispose of contents/container in accordance with local/regional/national/international regulation for hazardous wastes. Single Exposure Target Organs: Not applicable Repeated Exposure Target Organs: Not applicable (According to Directive 67/548/EEC)

Hazard pictograms

Xn, F

Hazard statements

R20/21/22: Harmful by inhalation, in contact with skin and if swallowed. R11: Highly Flammable.

Precautionary statements

S2: Keep out of the reach of children. S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S28: After contact with skin, wash immediately with plenty of soap and water.

2.3 Other hazards

Signs and Symptoms of Potential Overexposure: Pyridine is moderately to severely irritating to skin, eyes and mucous membranes. Vapors may be irritating to the respiratory tract. Pyridine is readily absorbed through the skin. Extended exposure (e.g. from saturated clothing) may lead to systemic poisoning. Symptoms may include headache, dizziness, drowsiness, nausea, and other effects. Symptoms seen after inhalation overexposures are expected to be essentially the same as those listed previously. Ingestion of several ounces of pyridine has resulted in severe vomiting, diarrhea, high fever, delirium and death. Ingestion is not likely to be a primary route of exposure.

Principle Routes of Exposure

Skin contact and absorption, eye contact, and inhalation. Ingestion is not likely to be a primary route of exposure.

Medical Conditions Generally Aggravated by Exposure

Persons with pre-existing skin, liver, or kidney disorders may be at increased risk from overexposure to this material. This is not likely to be a problem when appropriate procedures are used to minimize exposure.