BINDA BOTANICALS - TRADITIONAL SUNSCREEN FIRST NATIONS AUSTRALIAN SPF 50

SECTION 2: Hazards identification

Ingredient CAS No. Proportion (%w/w) Non-nano zinc oxide 1314-13-2 25.0 Other ingredients determined not to be hazardous n/a 75.0 Maximum Dermal Reference SED = LD50 LC50 NOAEL Margin of Reference concentration Absorpti Eprodu (mg/kg Safety (C) in % on % ct x bw/day MoS= C/100 x ) NOAEL/ Dap/10 SED 0 1. 25% Zinc Oxide - CAS # 1314-13-2 25.00 0.36 (Pirot F, 1996) 0.27 > 2000 mg/kg > 5.7 268.4 994.07407 (ECHA, n.d.-i; bw (Rat - mg/L/4 mg/kg/day Kim, 2017) Dermal) hrs (Rat - Oral) (Rat) 2. Sunflower Seed Oil - CAS # 8001-21-6 1.5 (ECHA, n.d.-c) 0.6 > 2000 mg/kg > 0.162 1000 mg/kg 1000 666.6667 (ECHA, n.d.-c) bw (Rat - mg/L/ bw/day (Rat) Dermal) air (Rat) 3. Jojoba Seed Oil - CAS # 90045-98-0 10.00 Default Dap 3 >= 5000 No data >= 500 mg/kg 500 166.6667 (ECHA, n.d.-e) for oils mg/kg bw bw (Guinea (Rat - Oral) pigs) 4. Thuja Plicata Extract - CAS # 499-44-5 5.00 (BasicMedical 0.015 500 mg/kg bw No data 5 mg/kg bw 5 333.3333 (Opinion of the Key, n.d.) (Rat - Oral) (Rats female Scientific - Oral) Committee on Food on Thujone, 2003) 5. Candelillia Wax - CAS # 8006-44-8 100.00 Default due to 18 > 5000 mg/kg No data 1900 mg/kg 1900 105.5555 (“Final Report lack of data bw (Rat - bw/day on the Safety Oral) Assessment of Candelillia Wax, Carnauba Wax, Japan Wax, and Beeswax” 1984) 6. Purified Water - CAS # 7732-18-5 100.00 Default due to 57 > 90000 No data None, safe 0 Safe MERCK SDS lack of data mg/kg [GRAS] bw/day (Rat - Oral) 7. Polyglyceryl-3 Polyricinoleate - CAS # 29894-35-7 / 235783-76-3 100.00 Default due to 6 > 5000 mg/kg No data 1000 mg/kg 1000 166.6667 (ECHA, n.d.-f) lack of data bw (Rat - bw/day (Rat Oral) - Oral) 8. Polyhydroxystearic Acid - CAS # 27924-99-8 100.00 Default due to 9 No data 1000 mg/hg 1000 111.1111 (Bergfeld et al., lack of data bw/day (Rat n.d.; “Scientific – Oral) from Opinion on the 9,10- Safety dihydroxyste Evaluation of aric acid the Substance oligomers Poly(12- (similar Hydroxystearic structure) Acid) Stearate, CAS No. 58128- 22-6 for Use in Food Contact Materials” 2010) Isostearic Acid CAS # 30399-84-9 100.00 Default due to > 2000 mg/kg No data 741 mg/kg 741 123.50000 (ECHA, n.d.-a) lack of data bw (Rat - bw/day (Rat Oral) - Oral) from similar compound 10. Calendula Extract CAS # 84776-23-8 10.00 (Andersen et 0.3 > 4640 mg/kg No data 50 mg/kg 50 166.66667 (Andersen et al., al., 2010) (Rat - Oral) bw/day (via 2010; Dhiva TTC and Lit) Cosmetics, 2016) 11. Xanthan Gum CAS # 11138-66-2 100.00 Default due to 15 > 5000 mg/kg No data 3301 mg/kg 3301 220.06667 (Mortensen et lack of data bw (Rats, bw/day al., 2017) Dogs - Oral) (male Rats - Oral) 12. Glycerin CAS # 56-81-5 10.00 _ (ECHA, n.d. 56750 mg/kg > 5.85 8000-10,000 8000 2666.6667 (ECHA, n.d.-d) bw (Guinea mg/L mg/kg bw pigs - Dermal) (Rat) (Rat - Oral) 13. Maltodextrin CAS # 9050-36-6 100.00 Default due to 90 mL/kg (Rat No data 4500 mg/kg 4500 1500 (PARCHEM SDS) lack of data - Oral) bw/day (Rat - Oral) 14. Potassium Cetyl Phosphate - CAS # 84861-79-0 / 19035-79-1 100.00 Default due to >2000 mg/kg No data 800 mg/kg 800 266.6667 MC Biotec lack of data bw (Rats - bw/day (Rat - MSDS Dermal) Oral) 15. Sodium Chloride CAS # 7647-14-5 100.00 Default due to >10000 > 45 2533 mg/kg 2533 844.3333 (ECHA, n.d.-g) lack of data mg/kg bw mg/L bw/day (Rat - (Rabbit - air (Rat) Oral) Dermal) 16. Sea Buckthorn CAS # 2252341-16-1 100.00 Default due to 240 LD50 > 10,000 No NOAEL = 100,000 416.67 (Rajkumar T.) lack of data mg/kg bw data 100,000 (rat-oral) mg/kg bw/day (Rat- Oral) 17. Sodium Hyaluronate CAS # 9067-32-7 100.00 Deafult due to > 5280 mg/kg No >=3462 3462 1154 (Bergfeld, lack of data bw (Rat - data mg/kg bw Donald, Belsito, Oral) (Rat) Cohen, Klaassen, Rettie, et al., n.d.; Oe et al., 2011) 18. Bisabolol CAS # 23089-26-1 100.00 Default due to 1.5 > 2000 mg/kg No 200 mg/kg 200 133.3333 (ECHA, n.d.-f) lack of data bw (Rat - data bw/day (Rat Oral) - Dermal) 19. Terminalia ferdinandiana (Kakadu Plum) Extract CAS # 1176234-54-0 100.00 Default due to 2840 mg/kg No No data (Kakadu Plum lack of data bw (Rat, data SDS) Oral) 20. Vitamin C (Sodium Ascorbate) - CAS # 134-03-2 100.00 Default due to 2000 mg/kg No 1000 mg/kg 1000 111.1111 (Dipalmitate et lack of data bw (Mice - data bw/day (Rats al., n.d.; Oral) - Oral) Fitzhugh & Nelson, 1946) 21. Vitamin E CAS # 59-02-9 100.00 Default due to > 5000 mg/kg No data 500 mg/kg 500 166.6667 (ECHA, n.d.-i) lack of data bw (Rabbit - bw/day (Rats Dermal) - Oral) 22. Coriandrum Sativum CAS # 84775-50-8 100.00 Default due to 1.59 LD50 > 3588 No 160 mg/kg 160 100.63 (ECHA, n.d.- lack of data mg/kg bw data bw/day (Rat- coriander) (rat-oral) Oral) 23. Citrus grandis CAS # 90045-43-5 100.00 Default due to 0.36 > 5000 mg/kg No data 1000 mg/kg 340 339.64 ECHA, n.d.-d) lack of data bw (Rats – bw/day on Oral) and males and >5000 mg/kg 340 mg/kg bw (Rabbit- bw/day in Dermal) females 24. Iron Oxide Black CAS # 12227-89-3 100.00 Default due to 0.30 > 10000 No data 100 mg/kg 100 333.3333 Lethal lack of data mg/kg bw bw/day Cosmetics (Rat - Oral) (Check lethal MSDS/Get value MSDS) of NOAEL from manufacturer 25. Iron Oxide Red CAS # 1309-37-1 100.00 Default due to 0.30 > 10000 > 5.0 > 1000 mg/kg 1000 333.3333 (ECHA, n.d.-a) lack of data mg/kg bw mg/L bw/day (Rat) (Rat - Oral) (Rat) 26. Iron Oxide Yellow CAS # 51274-00-1 100.00 Default due to 0.30 > 10000 > 5.0 > 1000 mg/kg 1000 333.3333 (ECHA, n.d.-d) lack of data mg/kg bw mg/L bw/day (Rat) (Rat - Oral) (Rat)