CutiBiome CLR

SECTION 2: Hazards identification

According to Regulation (EC) No. 1272/2008 (CLP) Classification of the substance or mixture

2.2 Label elements

According to EC directives or the corresponding national regulations the product does not have to be labelled.

Special rules for supplemental label elements for certain mixtures

EUH210 Safety data sheet available on request.

2.3 Other hazards

None

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 [CLP] None 2.2 Label elements According to EC directives or the corresponding national regulations the product does not have to be labelled. Labelling according to Regulation (EC) No. 1272/2008 [CLP] Special rules for supplemental label elements for certain mixtures EUH210 Safety data sheet available on request. 2.3 Other hazards None SECTION 3: Composition/information on ingredients 3.2 Mixtures Description CutiBiome CLR is a mixed lipophilic extract produced from piper nigrum seeds, manuka oil and magnolia bark. Hazardous ingredients MANUKA TRI-KETONE FRACTION ; REACH No. : 01-0000017203-81 Weight fraction : ≥ 1 - < 5 % Classification 1272/2008 [CLP] : Acute Tox. 4 ; H302 Skin Irrit. 2 ; H315 Eye Irrit. 2 ; H319 This mixture contains the following substances of very high concern (SVHC) which are included in the Candidate List according to Article 59 of REACH None This mixture contains the following substances of very high concern (SVHC) which are subject to authorisation according to Annex XIV of REACH None Additional information Full text of H- and EUH-phrases: see section 16. SECTION 4: First aid measures 4.1 Description of first aid measures Following inhalation Provide fresh air. In case of skin contact Water and soap After eye contact After contact with the eyes, rinse with water with the eyelids open for a sufficient length of time, then consult an ophthalmologist immediately. After ingestion Do NOT induce vomiting. 4.2 Most important symptoms and effects, both acute and delayed No information available. 4.3 Indication of any immediate medical attention and special treatment needed None SECTION 5: Firefighting measures 5.1 Extinguishing media Suitable extinguishing media Foam Carbon dioxide (CO2) Dry extinguishing powder Unsuitable extinguishing media Water 5.2 Special hazards arising from the substance or mixture Hazardous combustion products Carbon dioxide (CO2) Carbon monoxide Acrolein 5.3 Advice for firefighters Do not inhale explosion and combustion gases. 5.4 Additional information Do not allow run-off from fire-fighting to enter drains or water courses. SECTION 6: Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures No special measures are necessary. 6.2 Environmental precautions Do not allow to enter into surface water or drains. 6.3 Methods and material for containment and cleaning up Absorb with liquid-binding material (e.g. sand, diatomaceous earth, acid- or universal binding agents). 6.4 Reference to other sections None SECTION 7: Handling and storage 7.1 Precautions for safe handling Protective measures Measures to prevent fire Take precautionary measures against static discharges. 7.2 Conditions for safe storage, including any incompatibilities Hints on joint storage Storage class : 10 Storage class (TRGS 510) : 10 Further information on storage conditions Protect against : Contact with air/oxygen. UV-radiation/sunlight Storage temperature : 15 - 25 °C (59 - 77 °F) 7.3 Specific end use(s) None SECTION 8: Exposure controls/personal protection 8.1 Control parameters DNEL-/PNEC-values DNEL/DMEL No substance related limit value derivable. PNEC No substance related limit value derivable. 8.2 Exposure controls Personal protection equipment Eye/face protection Suitable eye protection Eye glasses with side protection Skin protection Hand protection Suitable gloves type : Disposable gloves. Suitable material : PE (polyethylene) NR (natural rubber, natural latex) NBR (Nitrile rubber) Thickness of the glove material : > 0.1 mm Respiratory protection Usually no personal respirative protection necessary. General information When using do not eat, drink, smoke, sniff. Minimum standard for preventive measures while handling with working materials are specified in the TRGS 500. SECTION 9: Physical and chemical properties 9.1 Information on basic physical and chemical properties Appearance Physical state : Liquid Colour : Yellowish Odour Poor, characteristic. Safety characteristics Initial boiling point and boiling ( 1013 hPa ) approx. 224 °C range : approx. Flash point : 189 °C Vapour pressure : ( 50 °C ) No data available Density : ( 20 °C ) 0,84 - 0,85 g/cm3 Solvent separation test : ( 20 °C ) No data available approx. Viscosity : ( 20 °C ) 45 mPa*s 9.2 Other information None SECTION 10: Stability and reactivity 10.1 Reactivity No information available. 10.2 Chemical stability No information available. 10.3 Possibility of hazardous reactions No information available. 10.4 Conditions to avoid No information available. 10.5 Incompatible materials No information available. 10.6 Hazardous decomposition products No information available. SECTION 11: Toxicological information 11.1 Information on toxicological effects CutiBiome CLR contains ingredients, which have a long tradition in plant medicine. CutiBiome CLR is considered to be non-toxic and safe in cosmetic use at the levels advised by us. Corrosion Skin corrosion/irritation Parameter : Skin corrosion/irritation Species : Human Result : Not irritant Method : Patch test Serious eye damage/eye irritation Parameter : Serious eye damage/eye irritation Species : hen's egg Result : Not irritant Method : HET-CAM Parameter : Serious eye damage/eye irritation Species : Bovine eye/corneal Result : UN GHS "No category" Method : OECD 437 CMR effects (carcinogenicity, mutagenicity and toxicity for reproduction) The ingredients in this mixture do not meet the criteria for classification as CMR category 1A or 1B according to CLP. Germ cell mutagenicity In vitro mutagenicity Parameter : Ames-Test Exposure route : In vitro mutagenicity Species : Salmonella typhimurium, 4 strains Result : Negative (with metabolic activation). Parameter : Ames-Test Exposure route : In vitro mutagenicity Species : E. coli WP2 uvrA Result : Negative (with metabolic activation). SECTION 12: Ecological information 12.1 Toxicity No information available. 12.2 Persistence and degradability Biodegradation Biodegradable. 12.3 Bioaccumulative potential No information available. 12.4 Mobility in soil No information available. 12.5 Results of PBT and vPvB assessment This substance does not meet the PBT/vPvB criteria of REACH, Annex XIII. 12.6 Other adverse effects No information available. 12.7 Additional ecotoxicological information None SECTION 13: Disposal considerations 13.1 Waste treatment methods No information available. SECTION 14: Transport information 14.1 UN number No dangerous good in sense of these transport regulations. 14.2 UN proper shipping name No dangerous good in sense of these transport regulations. 14.3 Transport hazard class(es) Land transport (ADR/RID)