Surflan A.S. Herbicide

SECTION 2: Hazards identification

EMERGENCY OVERVIEW Hazardous chemical. Opaque bright orange liquid with a slight aromatic odor. May cause eye and skin irritation. LD50 for skin absorption is >5000 mg/kg. Oral LD50 is >5000 mg/kg. Inhalation LC50 is >6.30 mg/L. Toxic to avian and aquatic organisms.

Potential health effects

This section includes possible adverse effects, which could occur if this material is not handled in the recommended manner. EYE: May cause slight temporary eye irritation. Corneal injury is unlikely. SKIN: Prolonged contact may cause skin irritation with local redness. Prolonged or frequently repeated skin contact may cause an allergic skin reaction in some individuals. Prolonged skin contact is unlikely to result in absorption of harmful amounts. The LD50 for skin absorption in rabbits is >5000 mg/kg. INGESTION: Very low toxicity if swallowed. The oral LD50 for rats and mice is 5000 mg/kg. Harmful effects not anticipated from swallowing small amounts. INHALATION: At room temperature, exposure to vapor is minimal low volatility; vapor from heated material may cause respiratory irritation and other effects. The LC50 for rats was >6.30 mg/L in 4 hours. SYSTEMIC (OTHER TARGET ORGAN) EFFECTS: Contains component(s) which, in animals, have been shown to cause liver, kidney, bladder, spleen or blood effects. For propylene glycol, in humans, symptoms may include central nervous system depression (headache, dizziness, drowsiness, and incoordination.

Cancer information

Thyroid follicular cell tumors observed in rats were considered a secondary response caused by mechanisms not relevant to humans. Benign skin and adnexal tumors observed in rats may also have been secondary to thyroid effects. TERATOLOGY (BIRTH DEFECTS): Oryzalin did not cause birth defects in animals; other fetal effects occurred only at doses toxic to the mother. REPRODUCTIVE EFFECTS: In animal studies, the majority of components did not interfere with reproduction. Reproductive effects seen in female animals are believed to be due to altered nutritional states resulting from extremely high doses of glycerin given in the diet. Similar effects have been seen in animals fed synthetic diets.