Donepezil Hydrochloride Tablets, 23mg

SECTION 2: Hazards identification

EMERGENCY OVERVIEW: Poison Adverse Effects: Adverse effects may include nausea, vomiting, abdominal pain, loss of appetite, diarrhea, constipation, urinary incontinence, sweating, salivation, tremor, unusual tiredness or weakness, difficulty sleeping, headache, dizziness, fainting, mood and mental disturbances, muscle or joint pain, unusual bleeding of bruising, and skin rash. Possible allergic reaction to material if inhaled, ingested or in contact with skin. Overdose Effects: Overdose of cholinesterase inhibitors can lead to cholinergic crisis characterized by severe nausea, vomiting, excessive salivation, sweating, slow heartbeat, low blood pressure, severe muscle weakness, respiratory depression, collapse, convulsions, coma, and death. Acute: Possible eye, skin, gastrointestinal and/ or respiratory tract irritation. Chronic: Possible hypersensitization.

Medical Conditions Generally Aggravated by Exposure

Hypersensitivity to material, peptic ulcers or history of, asthma or obstructive pulmonary disease, cardiovascular conduction disorders, gastrointestinal or urinary tract obstruction, Parkinson's disease, CYPZD6 deficiency, and seizure disorders. Cross Sensitivity: Persons sensitive to piperidine derivatives may be sensitive to this material as well. Target Organs: n/f For additional information on toxicity, see Section 11.