2’-O-(tert-Butyldimethylsilyl)-6α-hydroxy Paclitaxel

Toronto Research Chemicals

Revision date : 2014-06-24

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GHS05 GHS07 GHS08
Health risk rating 4
Safety risk rating 1
Environmental risk rating 1

General Information

Revision date

2014-06-24

Product name

2’-O-(tert-Butyldimethylsilyl)-6α-hydroxy Paclitaxel

Chemical name

2’-O-(tert-Butyldimethylsilyl)-6α-hydroxy Paclitaxel

CAS No.

211732-86-4

1.2.1 Relevant identified uses

To be used only for scientific research and development. Not for use in humans or animals

Emergency telephone

+14166659696 between 0800-1700 (GMT-5

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Company Information

company name

Toronto Research Chemicals

e-mail address of the competent person responsible for the Safety Data Sheet

orders@trc-canada.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H315, H317, H318, H335, H361

Hazard statements

Code

Statements

H315

Causes skin irritation

Section 2

SECTION 2: Hazards identification

HMIS Classification WHMIS Symbols (Canada)

WHMIS Classification

D2A Very Toxic Material Causing Other Toxic Effects D2B Reproductive Toxin/Teratogen Toxic Material Causing Other Toxic Effects Skin Sensitizer Severe Eye Irritant Moderate Skin/Respiratory Tract Irritant 2.1/2.2 Classification of the Substance or Mixture and Label Elements

Classification according to GHS

According to EU Regulation 1272/2008 and US OSHA 1910.1200) Reproductive Toxicity (Category 2) Sensitisation, Skin (Category 1) Skin Irritation (Category 2) Serious Eye Damage (Category 1) Specific Target Organ Toxicity, Single Exposure; Respiratory Tract Irritation (Category 3)

EU Classification

According to EU Regulation 67/548/EEC) Irritating to respiratory system and skin. Risk of serious damage to the eyes. May cause sensitization by skin contact. Possible risk of harm to the unborn child. Possible risk of impaired fertility. EU Risk and Safety Statements (According to EU Regulation 67/548/EEC)

Hazard statements

Harmful Xn Risk Codes and Phrases R37/38 Irritating to respiratory system and skin. R41 Risk of serious damage to the eyes. R43 May cause sensitization by skin contact. R63 Possible risk of harm to the unborn child. Possible risk of impaired fertility. R62 Identification (According to EU Regulation 1272/2008 and US OSHA 1910.1200) H361 Suspected of damaging fertility or the unborn child. H317 May cause an allergic skin reaction. H315 Causes skin irritation. H318 Causes serious eye damage. H335 May cause respiratory irritation.

Precautionary statements

Codes and Phrases S53 Avoid exposure - obtain special instruction before use. S26 After contact with skin, take off immediately all contaminated clothing and wash with plenty of S27/28 Wear suitable protective clothing, gloves and eye/face protection.soap and water. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. After contact with skin, take off immediately all contaminated clothing and wash with plenty of soap and water. P201 Obtain special instructions before use. P280 Wear protective gloves/protective clothing/eye protection/face protection. P302/P352 IF ON SKIN: Wash with plenty of soap and water P305/P351/P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P333/P313 If skin irritation or rash occurs: Get medical advice/attention.

Signal word

Danger

2.3 Other hazards

No data available

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