2-Debenzoyl Paclitaxel 2-Pentanoate

Toronto Research Chemicals

Revision date : 2012-09-19

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GHS05 GHS06 GHS07 GHS08
Health risk rating 4
Safety risk rating 1
Environmental risk rating 3

General Information

Revision date

2012-09-19

Product name

2-Debenzoyl Paclitaxel 2-Pentanoate

Substance name

2-Debenzoyl Paclitaxel 2-Pentanoate

Chemical name

Moderate eye irritant

CAS No.

153415-45-3

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Company Information

company name

Toronto Research Chemicals

e-mail address of the competent person responsible for the Safety Data Sheet

orders@trc-canada.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H301, H313, H315, H317, H318, H319, H331, H335, H361, H413

Hazard statements

Code

Statements

H301

Toxic if swallowed

Section 2

WHMIS Classification

D2A

Hazard statements

Very Toxic Material Causing Other Toxic Effects Reproductive hazard Moderate respiratory irritant H335 May cause respiratory irritation. Moderate eye irritant H331 H315 Causes skin irritation. H317 May cause an allergic skin reaction. H318 Causes serious eye damage. H335 May cause respiratory irritation. H361 Suspected of damaging fertility or the unborn child. H413 May cause long lasting harmful effects to aquatic life. Suitable extinguishing media

Signal word

H315 Danger Causes skin irritation. D2B Moderate skin irritant H319 Causes serious eye irritation. Danger

Precautionary statements

Toxic if inhaled. H301 Toxic if swallowed. Skin sensitiser P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. Mutagen H313 P302/P352 May be harmful in contact with skin. IF ON SKIN: Gently wash with plenty of soap and water. P305/P351/P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P280 Wear protective gloves/ eye protection/ face protection. Special protective equipment for fire-fighters P302/P352 IF ON SKIN: wash with plenty of soap and water. Wear self contained breathing apparatus for fire fighting if necessary. P305/P351/P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

Health hazards

2 P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray. P305/P351/P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact 2 Flammability: 1 If inhaled

Hazard pictograms

Flammability: 0 lenses if present and easy to do. Continue rinsing. Personal precautions Use personal protective equipment. Avoid dust or aerosol formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Environmental precautions

Physical hazards

0 P302/P352 IF ON SKIN: Wash with plenty of soap and water. General Advice Consult a physician. Show this safety data sheet to the doctor in attendance. Target Organs Move out of dangerous area. Cardiovascular system, Nerves, Eyes, Kidney, Liver, Bone marrow 0 If breathed in, move person into fresh air. If not breathing, give artificial respiration. Inhalation May be harmful if inhaled. Causes respiratory tract irritation. Consult a physician. Skin May be harmful if absorbed through skin. Causes skin irritation.

Potential health effects

Eyes Causes eye irritation. In case of skin contact Ingestion May be harmful if swallowed. Inhalation Toxic if inhaled. May cause respiratory tract irritation. Wash off with soap and plenty of water. Consult a physician. Ingestion Toxic if swallowed. Skin May be harmful if absorbed through skin. May cause skin irritation. In case of eye contact Skin irritation (Category 2) Eyes May cause eye irritation. Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. Serious eye damage (Category 1) Skin sensitization (Category 1) If swallowed Reproductive toxicity (Category 2) Never give anything by mouth to an unconscious person. Rinse mouth with water. Specific target organ toxicity - single exposure (Category 3) Consult a physician. Chronic aquatic toxicity (Category 4)

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