Note: Ingredients listed on restricted chemical lists
EC/CAS
57-57-8
Name of the chemical
Propiolactone
Concentration
>= 95 - <= 100
General Information
Version
1.2
Revision date
2025-11-14
Product name
β-Propiolactone
CAS No.
57-57-8
1.2.1 Relevant identified uses
For laboratory research purposes
Emergency telephone
+81-3-5640-8878, +81-3-5640-8902
Icons in SDS
Company Information
company name
TOKYO CHEMICAL INDUSTRY CO., LTD
e-mail address of the competent person responsible for the Safety Data Sheet
globalbusiness@tcichemicals.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H227, H301, H315, H318, H330, H335, H340, H351
Hazard statements
Code
Statements
H227
Combustible liquid
Section 2
SECTION 2: Hazards identification
GHS Classification GHS classification of chemical product Flammable liquids Category 4 Acute toxicity (Oral) Category 3 Acute toxicity (Inhalation) Category 1 Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 1 Germ cell mutagenicity Category 1B Carcinogenicity Category 2 Specific target organ toxicity - Category 3 (Respiratory tract irritation) single exposure
Signal word
Danger
Hazard statements
Combustible liquid. Toxic if swallowed. Causes skin irritation. Causes serious eye damage. Fatal if inhaled. May cause respiratory irritation. May cause genetic defects. Suspected of causing cancer.
Prevention
Obtain special instructions before use. Do not handle until all safety precautions have been read and under- stood. Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking. Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. Wash skin thoroughly after handling. Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/ protective clothing/ eye protection/ face pro- tection. Wear respiratory protection.
Response
IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth. IF ON SKIN: Wash with plenty of water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediate- ly call a POISON CENTER/ doctor. IF exposed or concerned: Get medical advice/ attention. If skin irritation occurs: Get medical advice/ attention. Take off contaminated clothing and wash it before reuse. In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.
Storage
Store in a well-ventilated place. Keep container tightly closed. Store in a well-ventilated place. Keep cool. Store locked up.
Disposal
Dispose of contents/ container to an approved waste disposal plant.
Other hazards which do not result in classification
None known.
2.1 Classification of the substance or mixture
Flammable liquids : Category 4 Acute toxicity (Oral) : Category 3 Acute toxicity (Inhalation) : Category 1 Skin corrosion/irritation : Category 2 Serious eye damage/eye irritation : Category 1 Germ cell mutagenicity : Category 1B Carcinogenicity : Category 2 Specific target organ toxicity - : Category 3 (Respiratory tract irritation) single exposure