β-Propiolactone

TOKYO CHEMICAL INDUSTRY CO., LTD

Revision date : 2025-11-14

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GHS05 GHS06 GHS08
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

57-57-8

Name of the chemical

Propiolactone

Concentration

>= 95 - <= 100

General Information

Version

1.2

Revision date

2025-11-14

Product name

β-Propiolactone

CAS No.

57-57-8

1.2.1 Relevant identified uses

For laboratory research purposes

Emergency telephone

+81-3-5640-8878, +81-3-5640-8902

Icons in SDS

GHS05 GHS06 GHS08

Company Information

company name

TOKYO CHEMICAL INDUSTRY CO., LTD

e-mail address of the competent person responsible for the Safety Data Sheet

globalbusiness@tcichemicals.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H227, H301, H315, H318, H330, H335, H340, H351

Hazard statements

Code

Statements

H227

Combustible liquid

Section 2

SECTION 2: Hazards identification

GHS Classification GHS classification of chemical product Flammable liquids Category 4 Acute toxicity (Oral) Category 3 Acute toxicity (Inhalation) Category 1 Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 1 Germ cell mutagenicity Category 1B Carcinogenicity Category 2 Specific target organ toxicity - Category 3 (Respiratory tract irritation) single exposure

Signal word

Danger

Hazard statements

Combustible liquid. Toxic if swallowed. Causes skin irritation. Causes serious eye damage. Fatal if inhaled. May cause respiratory irritation. May cause genetic defects. Suspected of causing cancer.

Prevention

Obtain special instructions before use. Do not handle until all safety precautions have been read and under- stood. Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking. Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. Wash skin thoroughly after handling. Do not eat, drink or smoke when using this product. Use only outdoors or in a well-ventilated area. Wear protective gloves/ protective clothing/ eye protection/ face pro- tection. Wear respiratory protection.

Response

IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth. IF ON SKIN: Wash with plenty of water. IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediate- ly call a POISON CENTER/ doctor. IF exposed or concerned: Get medical advice/ attention. If skin irritation occurs: Get medical advice/ attention. Take off contaminated clothing and wash it before reuse. In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.

Storage

Store in a well-ventilated place. Keep container tightly closed. Store in a well-ventilated place. Keep cool. Store locked up.

Disposal

Dispose of contents/ container to an approved waste disposal plant.

Other hazards which do not result in classification

None known.

2.1 Classification of the substance or mixture

Flammable liquids : Category 4 Acute toxicity (Oral) : Category 3 Acute toxicity (Inhalation) : Category 1 Skin corrosion/irritation : Category 2 Serious eye damage/eye irritation : Category 1 Germ cell mutagenicity : Category 1B Carcinogenicity : Category 2 Specific target organ toxicity - : Category 3 (Respiratory tract irritation) single exposure

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