Note: Ingredients listed on restricted chemical lists
EC/CAS
407-25-0
Name of the chemical
Trifluoroacetic anhydride
Concentration
>95
General Information
Version
8
Revision date
2026-07-16
Product name
Trifluoroacetic anhydride
Product Synonyms
TFAA
CAS No.
407-25-0
supplier name
Fisher Scientific UK
Emergency telephone
001-800-227-6701, +32 14 57 52 11, 001-201-796-7100, +32 14 57 52 99, 001-800-424-9300, 001-703-527-3887
Icons in SDS
Company Information
company name
Fisher Scientific UK
e-mail address of the competent person responsible for the Safety Data Sheet
begel.sdsdesk@thermofisher.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H314, H332, H361, H412
Hazard statements
Code
Statements
H314
Causes severe skin burns and eye damage
Section 2
SECTION 2: Hazards identification
Physical State
Appearance/Odor
Liquid Colorless pungent Emergency Overview Causes severe skin burns and eye damage. Harmful to aquatic life with long lasting effects. Harmful if inhaled. Suspected of damaging fertility or the unborn child. Reacts violently with water. Hygroscopic. Classification of the substance or mixture Acute Inhalation Toxicity - Vapors Category 4 Skin Corrosion/Irritation Category 1 A Serious Eye Damage/Eye Irritation Category 1 Reproductive Toxicity Category 2 Chronic aquatic toxicity Category 3 Label Elements
Signal word
Danger Hazard Statements H314 - Causes severe skin burns and eye damage H412 - Harmful to aquatic life with long lasting effects H332 - Harmful if inhaled H361 - Suspected of damaging fertility or the unborn child
Prevention
P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P264 - Wash face, hands and any exposed skin thoroughly after handling P271 - Use only outdoors or in a well-ventilated area P280 - Wear protective gloves/protective clothing/eye protection/face protection P273 - Avoid release to the environment
Response
P301 + P330 + P331 - IF SWALLOWED: rinse mouth. Do NOT induce vomiting P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor P363 - Wash contaminated clothing before reuse
Storage
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed
Disposal
P501 - Dispose of contents/ container to an approved waste disposal plant
Other physicochemical hazards
Reacts violently with water. Hygroscopic.
Health hazards
Corrosive. Causes skin and eye burns. Causes serious eye damage. Harmful if inhaled. Suspected of damaging fertility or the unborn child.
Environmental hazards
Harmful to aquatic life with long lasting effects. Reacts violently with water. Will likely be mobile in the environment due to its volatility. The product contains volatile organic compounds (VOC) which will evaporate easily from all surfaces.
2.3 Other hazards
Toxic to terrestrial vertebrates. This product does not contain any known or suspected endocrine disruptors.
2.1 Classification of the substance or mixture
Acute Inhalation Toxicity - Vapors Category 4 Skin Corrosion/Irritation Category 1 A Serious Eye Damage/Eye Irritation Category 1 Reproductive Toxicity Category 2 Chronic aquatic toxicity