Note: Ingredients listed on restricted chemical lists
EC/CAS
200-413-8
Name of the chemical
Methotrexate (INN)
Concentration
N/A
General Information
Version
5
Revision date
2023-10-13
Product name
Methotrexate
Product Synonyms
Amet; Glutamic acid, N-(p-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzol)-, L-
CAS No.
59-05-2
Emergency telephone
800-424-9300, 001-703-527-3887, 001-800-227-6701, +32 14 57 52 11, 001-201-796-7100, +32 14 57 52 99, 001-800-424-9300
Icons in SDS
Company Information
company name
Fisher Scientific UK
e-mail address of the competent person responsible for the Safety Data Sheet
begel.sdsdesk@thermofisher.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H301, H315, H319, H335, H340, H360FD
Hazard statements
Code
Statements
H301
Toxic if swallowed
Section 2
SECTION 2: Hazards identification
CLP Classification - According to GB-CLP Regulations UK SI 2019/720 and UK SI 2020/1567 Classification of the substance or mixture
Physical hazards
Based on available data, the classification criteria are not met
Health hazards
Acute oral toxicity Category 3 (H301) Skin Corrosion/Irritation Category 2 (H315) Serious Eye Damage/Eye Irritation Category 2 (H319) Germ Cell Mutagenicity Category 1B (H340) Reproductive Toxicity Category 1B (H360FD) Specific target organ toxicity - (single exposure) Category 3 (H335)
Environmental hazards
Based on available data, the classification criteria are not met Full text of Hazard Statements: see section 16
Signal word
Danger
Hazard statements
H301 - Toxic if swallowed H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation H340 - May cause genetic defects H360FD - May damage fertility. May damage the unborn child
Precautionary statements
P301 + P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P337 + P313 - If eye irritation persists: Get medical advice/attention P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P280 - Wear protective gloves/protective clothing/eye protection/face protection P332 + P313 - If skin irritation occurs: Get medical advice/attention Additional EU labelling Restricted to professional users
2.3 Other hazards
This product does not contain any known or suspected endocrine disruptors
2.1 Classification of the substance or mixture
CLP Classification - According to GB-CLP Regulations UK SI 2019/720 and UK SI 2020/1567 Physical hazards Based on available data, the classification criteria are not met Health hazards Acute oral toxicity Category 3 (H301) Skin Corrosion/Irritation Category 2 (H315) Serious Eye Damage/Eye Irritation Category 2 (H319) Germ Cell Mutagenicity Category 1B (H340) Reproductive Toxicity Category 1B (H360FD) Specific target organ toxicity - (single exposure) Category 3 (H335) Environmental hazards Based on available data, the classification criteria are not met Full text of Hazard Statements: see section 16
