Note: Ingredients listed on restricted chemical lists
EC/CAS
57-57-8
Name of the chemical
Propiolactone
Concentration
<=100
General Information
Version
8
Revision date
2026-09-28
Product name
beta-Propiolactone
Product Synonyms
2-Oxetanone
CAS No.
57-57-8
Emergency telephone
001-800-227-6701, +32 14 57 52 11, 001-201-796-7100, +32 14 57 52 99, 001-800-424-9300, 001-703-527-3887
Icons in SDS
Company Information
company name
Thermo Fisher Scientific Chemicals, Inc
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H350
Hazard statements
Code
Statements
H350
May cause cancer
Section 2
SECTION 2: Hazards identification
(29 CFR 1910.1200) Classification
Signal word
Danger Hazard Statements Combustible liquid Causes skin irritation Causes serious eye irritation Fatal if inhaled May cause cancer
Prevention
Obtain special instructions before use Do not handle until all safety precautions have been read and understood Do not breathe dust/fume/gas/mist/vapors/spray Use only outdoors or in a well-ventilated area Wear respiratory protection Wash face, hands and any exposed skin thoroughly after handling Wear eye/face protection Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking Keep cool Wear protective gloves/protective clothing/eye protection/face protection
Response
IF exposed or concerned: Get medical attention/advice Inhalation IF INHALED: Remove person to fresh air and keep comfortable for breathing Immediately call a POISON CENTER or doctor Skin IF ON SKIN: Wash with plenty of soap and water If skin irritation occurs: Get medical advice/attention Take off contaminated clothing Eyes IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If eye irritation persists: Get medical advice/attention Fire In case of fire: Use CO2, dry chemical, or foam to extinguish
Storage
Store locked up Store in a well-ventilated place. Keep container tightly closed
Disposal
Dispose of contents/container to an approved waste disposal plant
2.3 Other hazards
None identified
2.1 Classification of the substance or mixture
This chemical is considered hazardous according to [US] OSHA (29 CFR 1910.1200, 2024) Flammable liquids Category 4 Acute Inhalation Toxicity - Vapors Category 2 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Carcinogenicity