Note: Ingredients listed on restricted chemical lists
EC/CAS
57-57-8
Name of the chemical
Propiolactone
Concentration
<=100
General Information
Version
3
Revision date
2025-12-30
Product name
beta-Propiolactone
Product Synonyms
2-Oxetanone
CAS No.
57-57-8
1.2.2. Uses advised against
This product does not contain any substance(s) on the Illicit Drug Precursors/Reagents list
Emergency telephone
+613 9757 4559
Icons in SDS
Company Information
company name
ThermoFisher Scientific Australia Pty Ltd
e-mail address of the competent person responsible for the Safety Data Sheet
ANZinfo@thermofisher.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H315, H319, H330, H350
Hazard statements
Code
Statements
H315
Causes skin irritation
Section 2
SECTION 2: Hazards identification
Classified as hazardous according to criteria of Safe Work Australia. Classification under Safe Work Australia
Physical hazards
No hazards identified
Health hazards
Acute Inhalation Toxicity - Vapors Category 2 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Carcinogenicity Category 1B
Environmental hazards
No hazards identified
2.2 Label elements
Skull and Crossbones
Signal word
Danger
Hazard statements
H315 - Causes skin irritation H319 - Causes serious eye irritation H330 - Fatal if inhaled H350 - May cause cancer Combustible liquid
Precautionary statements
P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking P260 - Do not breathe dust/fume/gas/mist/vapors/spray P264 - Wash face, hands and any exposed skin thoroughly after handling P271 - Use only outdoors or in a well-ventilated area P280 - Wear eye protection/ face protection P284 - Wear respiratory protection P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish P302 + P352 - IF ON SKIN: Wash with plenty of soap and water P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P310 - Immediately call a POISON CENTER or doctor P362 + P364 - Take off contaminated clothing and wash it before reuse P403 + P233 - Store in a well-ventilated place. Keep container tightly closed P405 - Store locked up P501 - Dispose of contents/ container to an approved waste disposal plant
Further information
Toxic to terrestrial vertebrates This product does not contain any known or suspected endocrine disruptors
2.1 Classification of the substance or mixture
Classified as hazardous according to criteria of Safe Work Australia Physical hazards No hazards identified Health hazards Acute Inhalation Toxicity - Vapors Category 2 Skin Corrosion/Irritation Category 2 Serious Eye Damage/Eye Irritation Category 2 Carcinogenicity Category 1B Environmental hazards No hazards identified
