Albumin Standard Ingestion No specific data

SECTION 2: Hazards identification

Directive 1999/45/EC: Physical state Liquid. [Clear sparkling liquid.] Odor Odorless.

Principle Routes of Exposure

Eye contact. Inhalation. Ingestion.

Potential Acute Health Effects

Inhalation No known significant effects or critical hazards. Ingestion No known significant effects or critical hazards. Skin No known significant effects or critical hazards. Eyes No known significant effects or critical hazards. Inhalation Irritating to respiratory system. Ingestion No known significant effects or critical hazards. Skin Irritating to skin. Eyes Irritating to eyes. Potential chronic health effects

Potential chronic health

effects No known significant effects or critical hazards. Carcinogenicity No known significant effects or critical hazards. Mutagenicity No known significant effects or critical hazards. Contains material that can cause target organ damage. Carcinogenicity No known significant effects or critical hazards. 4/15/2011. 1/9 Life Science Research PO Box 117 Rockford, IL (815) 968-0747 www.thermo.com Pierce Biotechnology Inc. 3747 N. Meridian Road 61105 (815) 968-7316 Fax Micro BCA Reagent A (MA) Mutagenicity No known significant effects or critical hazards.

Teratogenic Effects

No known significant effects or critical hazards. Developmental effects No known significant effects or critical hazards. 11/25/2009. 7 Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Albumin Standard 2. Fertility effects No known significant effects or critical hazards. Over-exposure signs/symptoms Inhalation No specific data. Ingestion No specific data. Skin No specific data. Eyes No specific data. Medical conditions None known. aggravated by over- exposure The preparation is not classified as dangerous according to Directive 1999/45/EC and its amendments. Classification Not classified See toxicological information (section 11) Composition/information on ingredients Substance/preparation Preparation There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section First aid measures Inhalation Move exposed person to fresh air. Keep person warm and at rest If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel Get medical attention if symptoms occur If unconscious, place in recovery position and get medical attention immediately Maintain an open airway Loosen tight clothing such as a collar, tie, belt or waistband Ingestion Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous Do not induce vomiting unless directed to do so by medical personnel If vomiting occurs, the head should be kept low so that vomit does not enter the lungs Get medical attention if symptoms occur. Never give anything by mouth to an unconscious person If unconscious, place in recovery position and get medical attention immediately Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband Skin contact Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse Eye contact Thermo SCIENTIFIC Albumin Standard Fire-fighting measures Flammability of the product In a fire or if heated, a pressure increase will occur and the container may burst Extinguishing media Suitable Use an extinguishing agent suitable for the surrounding fire Not suitable None known Special exposure hazards Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire No action shall be taken involving any personal risk or without suitable training Hazardous combustion No specific data products Special protective Fire-fighters should wear appropriate protective equipment and self-contained breathing equipment for fire-fighters apparatus (SCBA) with a full face-piece operated in positive pressure mode Accidental release measures Personal precautions No action shall be taken involving any personal risk or without suitable training Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering Do not touch or walk through spilled material. Avoid breathing vapor or mist Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate Put on appropriate personal protective equipment (see section 8) Environmental precautions Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air) Large spill Stop leak if without risk. Move containers from spill area. Approach release from upwind Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations see section 13). Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product Note: see section for emergency contact information and section 13 for waste disposal Small spill Stop leak if without risk. Move containers from spill area Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor Handling and storage Handling Put on appropriate personal protective equipment (see section 8) Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous Do not reuse container Storage Store in accordance with local regulations Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage Do not store in unlabeled containers Use appropriate containment to avoid environmental contamination 11/25/2009 3/7 Biosciences Division 3747 N. Meridian Rd Rockford, IL 815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 815) 968-7316 Fax Europe No exposure limit value known Consult local authorities for acceptable exposure limits Recommended monitoring If this product contains ingredients with exposure limits, personal, workplace atmosphere procedures or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment Engineering measures No special ventilation requirements. Good general ventilation should be sufficient to control worker exposure to airborne contaminants If this product contains ingredients with exposure limits, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure below any recommended or statutory limits Hygiene measures Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location Personal protection Respiratory Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator Hands Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary Eyes Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts Skin Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product Environmental exposure Emissions from ventilation or work process equipment should be checked to ensure they controls comply with the requirements of environmental protection legislation In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels Physical and chemical properties Physical state Thermo SCIENTIFIC Albumin Standard 40. Stability and reactivity Chemical stability The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur Conditions to avoid No specific data Incompatible materials No specific data Hazardous decomposition Under normal conditions of storage and use, hazardous decomposition products should products not be produced Possibility of hazardous Will not occur reactions Toxicological information United States Acute toxicity Conclusion/Summary To the best of our knowledge, the toxicological properties of this product have not been thoroughly investigated Chronic toxicity Conclusion/Summary Not available Carcinogenicity Conclusion/Summary Not available Mutagenicity Conclusion/Summary Not available Teratogenicity Conclusion/Summary Not available Reproductive toxicity Conclusion/Summary Not available Europe Chronic effects No known significant effects or critical hazards Carcinogenicity No known significant effects or critical hazards Mutagenicity No known significant effects or critical hazards Teratogenicity No known significant effects or critical hazards Developmental effects No known significant effects or critical hazards Fertility effects No known significant effects or critical hazards Ecological information Environmental effects No known significant effects or critical hazards United States Aquatic ecotoxicity Conclusion/Summary Not available Other adverse effects No known significant effects or critical hazards 11/25/2009 5/7 Biosciences Division 3747 N. Meridian Rd Rockford, IL 815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 815) 968-7316 Fax Waste disposal The generation of waste should be avoided or minimized wherever possible. Dispose of surplus and non-recyclable products via a licensed waste disposal contractor Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers Hazardous waste Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC Disposal should be in accordance with applicable regional, national and local laws and regulations Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees Transport information Regulatory No known significant effects or critical hazards. Developmental effects Fertility effects No known significant effects or critical hazards. Target organs Contains material which causes damage to the following organs: eyes. Contains material which may cause damage to the following organs: lungs, mucous membranes, gastrointestinal tract, upper respiratory tract, skin. Over-exposure siqns/symptoms Inhalation Adverse symptoms may include the following: respiratory tract irritation coughing Ingestion No specific data. Skin Adverse symptoms may include the following: irritation redness Eyes Adverse symptoms may include the following: pain or irritation watering redness Medical conditions Pre-existing disorders involving any target organs mentioned in this MSDS as being at aggravated by over- risk may be aggravated by over-exposure to this product. exposure See toxicological information (Section 11)

UN Number

Proper shipping Classes PG information name DOT Classification Not regulated IATA-DGR Class Not available PG Packing group 15 Regulatory information United States HCS Classification Not regulated U.S. Federal regulations United States inventory (TSCA 8b): All components are listed or exempted SARA 302/304/311/312 extremely hazardous substances: No products were found SARA 302/304 emergency planning and notification: No products were found SARA 302/304/31 1/312 hazardous chemicals: No products were found SARA 311/312 MSDS distribution chemical inventory hazard identification: No products were found Clean Water Act (CWA) 307: No products were found Clean Water Act (CWA) 311: No products were found Clean Air Act (CAA) 112 accidental release prevention: No products were found Clean Air Act (CAA) 112 regulated flammable substances: No products were found Clean Air Act (CAA) 112 regulated toxic substances: No products were found Canada

Physical hazards

The customer is responsible for determining the PPE code for this material. National Fire Protection Association (U.S.A.) Flammability Health Instability Special Date of printing 11/25/2009. Issued 11/25/2009. Date of previous issue 5/5/2008. Version 1.02 F Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named supplier, nor any of its subsidiaries, assumes any liability whatsoever for the accuracy or completeness of the information contained herein. Final determination of suitability of any material is the sole responsibility of the user. All materials may present unknown hazards and should be used with caution. Although certain hazards are described herein, we cannot guarantee that these are the only hazards that exist. This product has been classified according to the hazard criteria of the CPR and the MSDS contains all the information required by the CPR. 11/25/2009. 7/7 Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Thermo The world beader SCIENTIFIC in serving science Micro BCA Reagent A (MA) 1. Product and company identification Product name Micro BCA Reagent A (MA) Supplier Thermo Fisher Scientific Manufacturer Thermo Fisher Scientific Pierce Biotechnology P.O. Box 117 Rockford, IL 61105 United States 815.968.0747 or 800.874.3723 Code 0023231 1884750 MSDS # 1423 Issued > 4/15/2011. Print date > 4/15/2011. Responsible name MSDS (Regulatory Specialist) In case of emergency CHEMTREC: Material uses Refer to the instruction 800.424.9300 booklet for proper and OUTSIDE US: intended use. Otherwise, 703.527.3887 contact supplier for specific applications. Product type Liquid. Emergency overview Physical state Liquid. Color Clear

Signal word

WARNING!

Hazard statements

CAUSES RESPIRATORY TRACT, EYE AND SKIN IRRITATION. CONTAINS MATERIAL THAT CAN CAUSE TARGET ORGAN DAMAGE.

Precautionary statements

Do not breathe vapor or mist. Use only with adequate ventilation. Do not eat, drink or smoke when using this product. Avoid contact with eyes, skin and clothing. Keep container tightly closed. Wash thoroughly after handling.

2.1 Classification of the substance or mixture

Composition/information on ingredients Substance/preparation : Preparation There are no ingredients or additional ingredients present which, within the current knowledge of the supplier and in the concentrations applicable, are classified as hazardous to health or the environment and hence require reporting in this section. \4 . First aid measures Inhalation : Move exposed person to fresh air. Keep person warm and at rest. If not breathing, if breathing is irregular or if respiratory arrest occurs, provide artificial respiration or oxygen by trained personnel. Get medical attention if symptoms occur. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. Ingestion : Wash out mouth with water. Remove dentures if any. Move exposed person to fresh air. Keep person warm and at rest. If material has been swallowed and the exposed person is conscious, give small quantities of water to drink. Stop if the exposed person feels sick as vomiting may be dangerous. Do not induce vomiting unless directed to do so by medical personnel. If vomiting occurs, the head should be kept low so that vomit does not enter the lungs. Get medical attention if symptoms occur. Never give anything by mouth to an unconscious person. If unconscious, place in recovery position and get medical attention immediately. Maintain an open airway. Loosen tight clothing such as a collar, tie, belt or waistband. Skin contact : Flush contaminated skin with plenty of water. Remove contaminated clothing and shoes. Get medical attention if symptoms occur. Wash clothing before reuse. Clean shoes thoroughly before reuse. Eye contact Thermo SCIENTIFIC | Albumin Standard E . Fire-fighting measures Flammability of the product In a fire or if heated, a pressure increase will occur and the container may burst. Extinguishing media Suitable Use an extinguishing agent suitable for the surrounding fire. Not suitable None known. Special exposure hazards Promptly isolate the scene by removing all persons from the vicinity of the incident if there is a fire. No action shall be taken involving any personal risk or without suitable training. Hazardous combustion No specific data. products Special protective Fire-fighters should wear appropriate protective equipment and self-contained breathing equipment for fire-fighters apparatus (SCBA) with a full face-piece operated in positive pressure mode. 6. Accidental release measures Personal precautions No action shall be taken involving any personal risk or without suitable training. Evacuate surrounding areas. Keep unnecessary and unprotected personnel from entering. Do not touch or walk through spilled material. Avoid breathing vapor or mist. Provide adequate ventilation. Wear appropriate respirator when ventilation is inadequate. Put on appropriate personal protective equipment (see section 8). Environmental precautions : Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Inform the relevant authorities if the product has caused environmental pollution (sewers, waterways, soil or air). Large spill : Stop leak if without risk. Move containers from spill area. Approach release from upwind. Prevent entry into sewers, water courses, basements or confined areas. Wash spillages into an effluent treatment plant or proceed as follows. Contain and collect spillage with non-combustible, absorbent material e.g. sand, earth, vermiculite or diatomaceous earth and place in container for disposal according to local regulations (see section 13). Dispose of via a licensed waste disposal contractor. Contaminated absorbent material may pose the same hazard as the spilled product. Note: see section 1 for emergency contact information and section 13 for waste disposal. Small spill : Stop leak if without risk. Move containers from spill area. Dilute with water and mop up if water-soluble or absorb with an inert dry material and place in an appropriate waste disposal container. Dispose of via a licensed waste disposal contractor. 7. Handling and storage Handling Put on appropriate personal protective equipment (see section 8). Eating, drinking and smoking should be prohibited in areas where this material is handled, stored and processed. Workers should wash hands and face before eating, drinking and smoking. Do not ingest. Avoid contact with eyes, skin and clothing. Avoid breathing vapor or mist. Keep in the original container or an approved alternative made from a compatible material, kept tightly closed when not in use. Empty containers retain product residue and can be hazardous. Do not reuse container. Storage : Store in accordance with local regulations. Store in original container protected from direct sunlight in a dry, cool and well-ventilated area, away from incompatible materials (see section 10) and food and drink. Keep container tightly closed and sealed until ready for use. Containers that have been opened must be carefully resealed and kept upright to prevent leakage. Do not store in unlabeled containers. Use appropriate containment to avoid environmental contamination. 11/25/2009. 3/7 Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Europe No exposure limit value known. Consult local authorities for acceptable exposure limits. Recommended monitoring If this product contains ingredients with exposure limits, personal, workplace atmosphere procedures or biological monitoring may be required to determine the effectiveness of the ventilation or other control measures and/or the necessity to use respiratory protective equipment. Engineering measures No special ventilation requirements. Good general ventilation should be sufficient to control worker exposure to airborne contaminants. If this product contains ingredients with exposure limits, use process enclosures, local exhaust ventilation or other engineering controls to keep worker exposure below any recommended or statutory limits. Hygiene measures : Wash hands, forearms and face thoroughly after handling chemical products, before eating, smoking and using the lavatory and at the end of the working period. Appropriate techniques should be used to remove potentially contaminated clothing. Wash contaminated clothing before reusing. Ensure that eyewash stations and safety showers are close to the workstation location. Personal protection Respiratory Use a properly fitted, air-purifying or air-fed respirator complying with an approved standard if a risk assessment indicates this is necessary. Respirator selection must be based on known or anticipated exposure levels, the hazards of the product and the safe working limits of the selected respirator. Hands : Chemical-resistant, impervious gloves complying with an approved standard should be worn at all times when handling chemical products if a risk assessment indicates this is necessary. Eyes : Safety eyewear complying with an approved standard should be used when a risk assessment indicates this is necessary to avoid exposure to liquid splashes, mists, gases or dusts. Skin Personal protective equipment for the body should be selected based on the task being performed and the risks involved and should be approved by a specialist before handling this product. Environmental exposure Emissions from ventilation or work process equipment should be checked to ensure they controls comply with the requirements of environmental protection legislation. In some cases, fume scrubbers, filters or engineering modifications to the process equipment will be necessary to reduce emissions to acceptable levels. 9. Physical and chemical properties Physical state Thermo SCIENTIFIC | Albumin Standard 40. Stability and reactivity Chemical stability : The product is stable. Under normal conditions of storage and use, hazardous polymerization will not occur. Conditions to avoid : No specific data. Incompatible materials : No specific data. Hazardous decomposition : Under normal conditions of storage and use, hazardous decomposition products should products not be produced. Possibility of hazardous : Will not occur. reactions 11. Toxicological information United States Acute toxicity Conclusion/Summary : To the best of our knowledge, the toxicological properties of this product have not been thoroughly investigated. Chronic toxicity Conclusion/Summary : Not available. Carcinogenicity Conclusion/Summary : Not available. Mutagenicity Conclusion/Summary : Not available. Teratogenicity Conclusion/Summary : Not available. Reproductive toxicity Conclusion/Summary : Not available. Europe Chronic effects : No known significant effects or critical hazards. Carcinogenicity : No known significant effects or critical hazards. Mutagenicity : No known significant effects or critical hazards. Teratogenicity : No known significant effects or critical hazards. Developmental effects : No known significant effects or critical hazards. Fertility effects : No known significant effects or critical hazards. 12 . Ecological information Environmental effects : No known significant effects or critical hazards. United States Aquatic ecotoxicity Conclusion/Summary : Not available. Other adverse effects : No known significant effects or critical hazards. 11/25/2009. 5/7 Biosciences Division 3747 N. Meridian Rd. Rockford, IL (815) 968-0747 www.thermo.com/pierce Pierce PO Box 117 61105 (815) 968-7316 Fax Waste disposal : The generation of waste should be avoided or minimized wherever possible. Dispose of * surplus and non-recyclable products via a licensed waste disposal contractor. Disposal of this product, solutions and any by-products should at all times comply with the requirements of environmental protection and waste disposal legislation and any regional local authority requirements. Avoid dispersal of spilled material and runoff and contact with soil, waterways, drains and sewers. Hazardous waste : Within the present knowledge of the supplier, this product is not regarded as hazardous waste, as defined by EU Directive 91/689/EEC. Disposal should be in accordance with applicable regional, national and local laws and regulations. Refer to Section 7: HANDLING AND STORAGE and Section 8: EXPOSURE CONTROLS/PERSONAL PROTECTION for additional handling information and protection of employees. 14. Transport information Regulatory UN number Proper shipping Classes PG* information name DOT Classification Not regulated. IATA-DGR Class Not available. - PG* : Packing group 15 . Regulatory information United States HCS Classification : Not regulated. U.S. Federal regulations : United States inventory (TSCA 8b): All components are listed or exempted. SARA 302/304/311/312 extremely hazardous substances: No products were found. SARA 302/304 emergency planning and notification: No products were found. SARA 302/304/31 1/312 hazardous chemicals: No products were found. SARA 311/312 MSDS distribution - chemical inventory - hazard identification: No products were found. Clean Water Act (CWA) 307: No products were found. Clean Water Act (CWA) 311: No products were found. Clean Air Act (CAA) 112 accidental release prevention: No products were found. Clean Air Act (CAA) 112 regulated flammable substances: No products were found. Clean Air Act (CAA) 112 regulated toxic substances: No products were found. Canada WHMIS (Canada) : Not controlled under WHMIS (Canada). Canadian lists : Thermo SCIENTIFIC Albumin Standard 15 . Regulatory information EU regulations Risk phrases : This product is not classified according to EU legislation. International requlations International lists : Australia inventory (AICS): All components are listed or exempted. China inventory (IECSC): All components are listed or exempted. Korea inventory (KECI): All components are listed or exempted. Philippines inventory (PICCS): All components are listed or exempted. Japan inventory (ENCS): Not determined. 16. Other information Label requirements : NOT EXPECTED TO PRODUCE SIGNIFICANT ADVERSE HEALTH EFFECTS WHEN THE RECOMMENDED INSTRUCTIONS FOR USE ARE FOLLOWED. Hazardous Material Information System (U.S.A.) Health Flammability Physical hazards The customer is responsible for determining the PPE code for this material. National Fire Protection Association (U.S.A.) Flammability Health Instability Special Date of printing : 11/25/2009. Date of issue : 11/25/2009. Date of previous issue : 5/5/2008. Version : 1.02 F Indicates information that has changed from previously issued version. Notice to reader To the best of our knowledge, the information contained herein is accurate. However, neither the above-named