Note: Ingredients listed on restricted chemical lists
EC/CAS
123-91-1
Name of the chemical
1,4-Dioxane
Concentration
>95
General Information
Revision date
2026-06-25
Product name
1,4-Dioxane Reference Standard
Product Synonyms
Diox
CAS No.
123-91-1
Emergency telephone
+(60)-327884561
Icons in SDS
Company Information
company name
Thermo Fisher Scientific Fisher Scientific (M) Sdn Bhd
e-mail address of the competent person responsible for the Safety Data Sheet
laboratorysolution@thermofisher.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H225, H319, H335, H350
Hazard statements
Code
Statements
H225
Highly Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
Classification of the substance or mixture
Physical hazards
Flammable liquids Category 2 (H225)
Health hazards
Serious Eye Damage/Eye Irritation Category 2 (H319) Carcinogenicity Category 1B (H350) Specific target organ toxicity - (single exposure) Category 3 (H335)
Environmental hazards
Based on available data, the classification criteria are not met
Signal word
Danger
Hazard statements
H225 - Highly flammable liquid and vapor H319 - Causes serious eye irritation H335 - May cause respiratory irritation H350 - May cause cancer
Prevention
P201 - Obtain special instructions before use P202 - Do not handle until all safety precautions have been read and understood P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking P240 - Ground and bond container and receiving equipment P241 - Use explosion-proof electrical/ ventilating/ lighting equipment P242 - Use non-sparking tools P243 - Take action to prevent static discharges P280 - Wear eye protection/ face protection P261 - Avoid breathing dust/fume/gas/mist/vapors/spray P264 - Wash face, hands and any exposed skin thoroughly after handling P271 - Use only outdoors or in a well-ventilated area
Response
P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower P304 + P340 - IF INHALED: Remove person to fresh air and keep comfortable for breathing P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P308 + P313 - IF exposed or concerned: Get medical advice/attention P370 + P378 - In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish
Storage
P403 + P233 - Store in a well-ventilated place. Keep container tightly closed
Disposal
P501 - Dispose of contents/ container to an approved waste disposal plant
2.3 Other hazards
EUH019 - May form explosive peroxides EUH066 - Repeated exposure may cause skin dryness or cracking Toxic to terrestrial vertebrates Contains a known or suspected endocrine disruptor Included in the list established in accordance with Article 59(1) for having endocrine disrupting properties
2.1 Classification of the substance or mixture
Physical hazards Flammable liquids Category 2 (H225) Health hazards Serious Eye Damage/Eye Irritation Category 2 (H319) Carcinogenicity Category 1B (H350) Specific target organ toxicity - (single exposure) Category 3 (H335) Environmental hazards Based on available data, the classification criteria are not met