NORKOOL(TM) Inhibitor 231

SECTION 2: Hazards identification

OSHA Hazards Emergency Overview Color: Yellow Physical State: Liquid Odor: Pungent Hazards of product: WARNING! Harmful or fatal if swallowed. May cause eye irritation. May cause skin irritation. Isolate area. Highly toxic to fish and/or other aquatic organisms. OSHA Hazard Communication Standard This product is a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 CFR 1910.1200.

Potential health effects

Eye Contact: May cause slight eye irritation. May cause slight temporary corneal injury. Mist may cause eye irritation. Skin Contact: Prolonged contact may cause skin irritation with local redness. Skin Absorption: Prolonged skin contact is unlikely to result in absorption of harmful amounts. Repeated skin exposure to large quantities may result in absorption of harmful amounts. Massive * Indicates a Trademark Daqe i ofin contact with damaged skin or of material sufficiently hot to burn skin may result in absorption of potentially lethal amounts. Inhalation: At room temperature, exposure to vapor is minimal due to low volatility. With good ventilation, single exposure is not expected to cause adverse effects. If material is heated or areas are poorly ventilated, vapor/mist may accumulate and cause respiratory irritation and symptoms such as headache and nausea. Ingestion: Oral toxicity is expected to be moderate in humans due to ethylene glycol even though tests with animals show a lower degree of toxicity. Small amounts swallowed incidentally as a result of normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause serious injury, even death. May cause nausea and vomiting. May cause abdominal discomfort or diarrhea. Excessive exposure may cause central nervous system effects, cardiopulmonary effects (metabolic acidosis), and kidney failure. May cause methemoglobinemia, thereby impairing the blood's ability to transport oxygen. Effects of Repeated Exposure: Repeated excessive exposure may cause irritation of the upper respiratory tract. The data presented are for the following material: Ethylene glycol. In humans, effects have been reported on the following organs: Central nervous system. Observations in humans include: Nystagmus (involuntary eye movement). In animals, effects have been reported on the following organs: Kidney. Liver. For the minor component(s): Sodium nitrite. May cause methemoglobinemia, thereby impairing the blood's ability to transport oxygen. In animals, effects have been reported on the following organs: Testes. Heart. Lung. Spleen. Gastrointestinal tract.

Cancer information

Sodium nitrite has produced tumors in laboratory animals only at high doses; low dietary doses did not cause cancer in laboratory animals. It has caused tumors in animals when given in combination with secondary amines or disulfiram (for treatment of alcoholism). Persons on disulfiram (ANTABUSE) therapy with possible exposure to nitrites should seek medical advice. Birth Defects/Developmental Effects For the minor component(s) Sodium nitrite Has been toxic to the fetus in lab animals at doses toxic to the mother. Based on animal studies, ingestion of very large amounts of ethylene glycol appears to be the major and possibly only route of exposure to produce birth defects. Exposures by inhalation or skin contact, the primary routes of occupational exposure, had minimal effect on the fetus, in animal studies. In laboratory animals, boron compounds have caused birth defects only at doses toxic to the mother and have been toxic to the fetus at doses nontoxic to the mother. Reproductive Effects: Ingestion of large amounts of ethylene glycol has been shown to interfere with reproduction in animals. For the minor component(s): Sodium nitrite. In animal studies, has been shown to interfere with fertility.