Note: Ingredients listed on restricted chemical lists
EC/CAS
231-791-2/7732-18-5
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
N/A
General Information
Revision date
2012-12-04
Product name
VINCASAR PFS (VINCRISTINE SULFATE) INJECTION
Chemical name
Vincaleukoblastine, 22-oxo-, sulfate (1 1) (salt)
1.2.2. Uses advised against
Other than Relevant Use
Manufacturer Name
TEVA
Emergency telephone
1-800/424-9300, 01-703-527-3887
Icons in SDS
Company Information
company name
TEVA
e-mail address of the competent person responsible for the Safety Data Sheet
TevaSDSRequest@tevapharm.com
Section 2
SECTION 2: Hazards identification
Product definition
This product is a clear, colorless aqueous solution. Health Hazards WARNING! THIS PRODUCT CONTAINS A CYTOTOXIC AGENT. EXPOSURE BY ALL ROUTES OF EXPOSURE MUST BE AVOIDED. In the workplace, may be harmful by inhalation and eye or skin contact. May be harmful by ingestion and injection. There are scientific studies that suggest that personnel (e.g. nurses, pharmacists, etc.) who prepare and administer parenteral antineoplastics (e.g. in hospitals) may be at some risk due to potential mutagenicity,
Teratogenic Effects
and/or carcinogenicity of these materials if workplace exposures are not properly controlled. The actual risk in the workplace is not known. In therapeutic use, the most common adverse effects have been diarrhea, anorexia, nausea and vomiting. May also cause allergic reaction including anaphylactoid reaction. In therapeutic use, this material has caused adverse effects on the blood system, bone marrow, digestive, respiratory, neurological and reproductive systems. The most common adverse reaction is hair loss; the most troublesome adverse reactions are neuromuscular in origin. May cause harm to fetus during pregnancy. Limited evidence of adverse effects on fertility in both genders. Limited evidence of carcinogenic effects. These effects may be possible as a result of workplace exposure. Refer to
TOXICOLOGICAL INFORMATION
for additional information on adverse effects. Flammability Hazards This product is not flammable or combustible. When involved in a fire, this product may decompose and produce irritating vapors and toxic compounds (including carbon, sulfur and nitrogen oxides). Reactivity Hazards: This product is not reactive.
Environmental hazards
The active ingredient of this product is harmful to aquatic organisms and may cause harm to animals and aquatic organisms if accidentally released to the environment. Emergency Recommendations: Emergency responders must wear personal protective equipment suitable for the situation to which they are responding.
