Methotrexate Tablets Trexall (methotrexate tablets, USP)

SECTION 2: Hazards identification

Product definition

This product consists of oval, odorless tablets that are yellow (2.5 mg), green (5 mg), blue (7.5 mg), pink (10 mg) or purple (15 mg). Health Hazards In the workplace, exposure via inhalation and skin contact may cause irritation. Eye contact can cause mechanical irritation. In therapeutic use, the most common adverse effects of oral dosage have been nausea and vomiting, gastrointestinal bleeding. More serious hematological and digestive system effects have been reported. May cause harm to the fetus and have adverse effects on fertility for both genders. Serious allergic reactions have occurred when administered for therapeutic use. These effects may be possible as a result of workplace exposure. Refer to Section 11 (Toxicological Information) for additional information on adverse effects. Flammability Hazards: This product requires substantial pre-heating before ignition occurs. When involved in a fire, this product may decompose and produce irritating vapors and toxic compounds (including carbon, magnesium, silicon, sodium and nitrogen oxides). Reactivity Hazards: This product is not reactive.

Environmental hazards

Negligible. Emergency Recommendations Emergency responders must wear personal protective equipment suitable for the situation to which they are responding.