Encompass Herbicide

SECTION 2: Hazards identification

EMERGENCY OVERVIEW CAUTION • Harmful if inhaled or absorbed through skin. • Avoid breathing dust or spray mist. • Avoid contact with eyes, skin and clothing. • Keep out of reach of children.

Potential health effects

Acute Toxicity (Primary Routes of Exposure) Signs and Symptoms of Systemic Effects: No signs or symptoms occured in animals exposed to high oral or dermal doses of Flumioxazin Technical. Exposure to very high concentrations of Flumioxazin Technical in the air resulted in breathing difficulties, decreased activity and some changes in the tissues of the respiratory system. Acute Eye Contact: Based on an evaluation of the ingredients and/or similar products, this product may cause brief and/or minor eye irritation. The expected adverse health effects resulting from an exposure may include redness and possible swelling. Acute Skin Contact: Based on an evaluation of the ingredients and/or similar products, this product may cause brief and/or minor skin irritation. The expected adverse health effects resulting from an exposure may include redness and possibly some minor swelling. This product may be slightly toxic when absorbed through the skin. This product is not expected to cause allergic skin reactions. Acute Ingestion: Based on an evaluation of the ingredients and/or similar products, this product may be minimally toxic when ingested. Acute Inhalation: Based on an evaluation of the ingredients and/or similar products, this product is expected to be slightly toxic when inhaled. Exposure to high concentrations of dust may result in respiratory irritation. Signs and symptoms may include, but not be limited to, nasal discharge, sore throat, coughing and difficulty in breathing. Chronic Toxicity (including cancer): Repeated exposures to Flumioxazin Technical in animals have produced anemia and other blood formation changes, organ weight changes and changes in blood chemistry. Flumioxazin Technical did not produce cancer in life-time feeding studies in laboratory animals. This material contains a small amount of crystalline silica. Repeated inhalation of large amounts of silica dust over an extended period of time may result in a progressive, disabling disease, silicosis. Symptoms include shortness of breath, chest pain and reduced lung function. The International Agency for Research on Cancer (IARC) has determined that respirable crystalline silica is carcinogenic to humans. The National Toxicology Program (NTP) classifies respirable crystalline silica as a known carcinogen. Developmental Toxicity (birth defects): Birth defects were produced in the offspring of female rats exposed to Flumioxazin Technical. No effects were observed in rabbits. Reproductive Toxicity: Reproductive effects were observed in rats exposed to Flumioxazin Technical. Potentially Aggravated Medical Conditions: Individuals with anemia or preexisting diseases of the blood may have increased susceptibility to the toxicity of excessive exposures. For complete discussion of the toxicology data from which this evaluation was made, refer to Section 11. For Regulatory Information, refer to Section 15.