TS-3

SECTION 2: Hazards identification

EMERGENCY OVERVIEW • Colorless liquid. Irritating odor. Toxic fumes are released in fire situations. Causes eye irritation. Harmful if inhaled. May cause skin irritation. Clear all personnel from area. Aspiration hazard. Can enter lungs and cause damage to body systems. * •

Potential health effects

MSDS TEKMAR TS-3 Page - 1 - EYES May cause pain disproportionate to the level of irritation to eye tissues. May cause moderate eye irritation which may be slow to heal. May cause slight corneal injury. Vapor may cause eye irritation experienced as mild discomfort and redness. . SKIN: Prolonged or repeated exposure may cause skin irritation, even a burn. Repeated contact may cause drying or flaking of skin. May cause more severe response on covered skin (under clothing, gloves) Prolonged skin contact is unlikely to result in absorption of harmful amounts. INGESTION Low toxicity if swallowed. Small amounts swallowed incidental to normal handling operations are not likely to cause injury; however, swallowing larger amounts may cause injury. Aspiration into the lungs may occur during ingestion or vomiting resulting in rapid absorption and injury to other body systems. INHALATION: In confined or poorly ventilated areas, vapors can readily accumulate and can cause unconsciousness and death. Excessive exposure may cause irritation to upper respiratory tract (nose and throat). May cause carboxyhemoglobinemia, thereby impairing the blood's ability to transport oxygen. Minimal anesthetic or narcotic effects may be seen in the range of 500-1000 ppm methylene chloride. Progressively higher levels over 1000 ppm can cause dizziness, drunkenness, and as low as 10,000 ppm, unconsciousness and death. These high levels may also cause cardiac arrhythmias (irregular heartbeats). SYSTEMIC (OTHER TARGET ORGAN) EFFECTS: In animals, effects have been reported on the following organs: central nervous system, kidney and liver. May cause carboxyhemoglobinemia, thereby impairing the blood's ability to transport oxygen. TARGET ORGAN STATEMENT In animals, effects have been reported on the following organs central nervous system, kidney and liver. May cause carboxyhemoglobinemia, thereby impairing the blood's ability to transport oxygen. CARCINOGENICITY: For hazard communication purposes, under OSHA Standard 29 CFR Part 1910.1200, this chemical is listed as a potential carcinogen by IARC and NTP. Dichloromethane has been shown to increase the incidence of malignant tumors in mice and benign tumors in rats. Studies have shown that tumors observed in mice are unique to that species. Other animal studies, as well as several human epidemiology studies, failed to show a tumorigenic response. Dichloromethane is not believed to pose a measurable carcinogenic risk to man when handled as recommended. TERATOLOGY (BIRTH DEFECTS): Birth defects are unlikely. Exposures having no effect on the mother should have no effect on the fetus. Did not cause birth defects in animals; other effects were seen in the fetus only at doses which caused toxic effects to the mother. REPRODUCTIVE TOXICITY In animal studies, did not interfere with reproduction.