Trimethylsilyldiazomethane (ca. 10% in Hexane, ca. 0.6mol/L)

Hazard statements (CLP)

H225, H304, H315, H319, H335, H336, H361, H372, H411

Code

Statements

H225

Highly Flammable liquid and vapour

SECTION 2: Hazards identification

GHS Classification Emergency Overview Appearance : liquid Color : yellow Highly flammable liquid and vapor. May be fatal if swallowed and enters airways. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May cause drowsiness or dizziness. Suspect- ed of damaging fertility or the unborn child. Causes damage to organs through prolonged or repeated expo- sure. Toxic to aquatic life with long lasting effects. GHS Classification Flammable liquids Category 2 Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 2A Reproductive toxicity Category 2 Specific target organ toxicity - Category 3 (respiratory tract irritation, Narcotic effects) single exposure Specific target organ toxicity - Category 1 repeated exposure

Aspiration hazard

Category 1 Short-term (acute) aquatic hazard Category 2 Long-term (chronic) aquatic haz- ard Category 2

Signal word

Danger

Hazard statements

H225 Highly flammable liquid and vapor. H304 May be fatal if swallowed and enters airways. H315 Causes skin irritation. H319 Causes serious eye irritation. H335 May cause respiratory irritation. H336 May cause drowsiness or dizziness. H361 Suspected of damaging fertility or the unborn child. H372 Causes damage to organs through prolonged or repeated expo- sure. H411 Toxic to aquatic life with long lasting effects.

Prevention

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P210 Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking. P233 Keep container tightly closed. P240 Ground/bond container and receiving equipment. P241 Use explosion-proof electrical/ ventilating/ lighting/ equipment. P242 Use only non-sparking tools. P243 Take precautionary measures against static discharge. P260 Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

Response

P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower. P304 + P340 + P312 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER/ doctor if you feel unwell. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P331 Do NOT induce vomiting. P332 + P313 If skin irritation occurs: Get medical advice/ attention. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 + P364 Take off contaminated clothing and wash it before reuse. P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol- resistant foam to extinguish. P391 Collect spillage.

Storage

P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P403 + P235 Store in a well-ventilated place. Keep cool. P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant.

Other physicochemical hazards

Highly flammable liquid and vapor

Health hazards

Causes skin irritation. Causes serious eye irritation. Suspected of damaging fertility or the unborn child. May cause drowsiness or dizziness. May cause respiratory irritation. Causes damage to organs through pro- longed or repeated exposure. May be fatal if swallowed and enters airways

Environmental hazards

Toxic to aquatic life. Toxic to aquatic life with long lasting effects. 2 / 9

Other hazards which do not result in classification

None known.

2.1 Classification of the substance or mixture

Flammable liquids : Category 2 Skin corrosion/irritation : Category 2 Serious eye damage/eye irritation : Category 2A Reproductive toxicity : Category 2 Specific target organ toxicity - : Category 3 (respiratory tract irritation, Narcotic effects) single exposure Specific target organ toxicity - : Category 1 repeated exposure Aspiration hazard : Category 1 Short-term (acute) aquatic hazard : Category 2 Long-term (chronic) aquatic haz- : Category 2 ard