Methylenediphenyl 4,4"-Diisocyanate

Hazard statements (CLP)

H315, H317, H319, H330, H334, H335, H351, H370, H372

Code

Statements

H315

Causes skin irritation

SECTION 2: Hazards identification

Emergency Overview Appearance : Solid form Color : white Causes skin irritation. May cause an allergic skin reaction. Causes serious eye irritation. Fatal if inhaled. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause respiratory irritation. Suspected of causing cancer. Causes damage to organs (Respiratory system). Causes damage to organs through prolonged or repeated exposure. GHS Classification Acute toxicity (Inhalation) Category 2 Skin corrosion/irritation Category 2 Serious eye damage/eye irritation Category 2A Respiratory sensitization Category 1 Skin sensitization Category 1 Carcinogenicity Category 2 Specific target organ toxicity - Category 1 (Respiratory system) single exposure Specific target organ toxicity - Category 3 (respiratory tract irritation) single exposure Specific target organ toxicity - Category 1 repeated exposure

Signal word

Danger

Hazard statements

H315 Causes skin irritation. H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H330 Fatal if inhaled. H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled. H335 May cause respiratory irritation. H351 Suspected of causing cancer. H370 Causes damage to organs (Respiratory system). H372 Causes damage to organs through prolonged or repeated expo- sure.

Prevention

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust/ fume/ gas/ mist/ vapors/ spray. P264 Wash skin thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P271 Use only outdoors or in a well-ventilated area. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P284 Wear respiratory protection.

Response

P302 + P352 IF ON SKIN: Wash with plenty of water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P311 IF exposed or concerned: Call a POISON CENTER/ P333 + P313 If skin irritation or rash occurs: Get medical advice/ atten- tion. P337 + P313 If eye irritation persists: Get medical advice/ attention. P362 + P364 Take off contaminated clothing and wash it before reuse.

Storage

P403 + P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.

Disposal

P501 Dispose of contents/ container to an approved waste disposal plant.

Other physicochemical hazards

Not classified based on available information.

Health hazards

Fatal if inhaled. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. Suspected of causing cancer. Causes damage to organs. May cause respiratory irritation. Causes damage to organs through prolonged or repeat- ed exposure.

Environmental hazards

Not classified based on available information

Other hazards which do not result in classification

None known.

2.1 Classification of the substance or mixture

Acute toxicity (Inhalation) : Category 2 Skin corrosion/irritation : Category 2 Serious eye damage/eye irritation : Category 2A Respiratory sensitization : Category 1 Skin sensitization : Category 1 Carcinogenicity : Category 2 Specific target organ toxicity - : Category 1 (Respiratory system) single exposure Specific target organ toxicity - : Category 3 (respiratory tract irritation) single exposure Specific target organ toxicity - : Category 1 repeated exposure