Lithium Tri-sec-butylborohydride

Potential Acute Health Effects

Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested. Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

Potential chronic health

CARCINOGENIC EFFECTS : Not available. MUTAGENIC EFFECTS : Not available.

Teratogenic Effects

TUMORIGENIC EFFECTS Tetrahydrofuran: Rat TCLo (inhalation) 18900mg/kg/105 Weeks, intermittent. Toxic Effects: Tumorigenic- Equivocal tumorigenic agent by RTECS criteria. Kidney, Ureter, and Bladder- Kidney tumors. Rat TCLo (inhalation) 1800ppm/6 Hours/2 Years, intermittent. Tumorigenic- Equivocal tumorigenic agent by RTECS criteria. Kidney, Ureter, and Bladder- Tumors. Mouse TCLo (inhalation) 113400mg/kg/105 Weeks, intermittent. Toxic Effects: Tumorigenic- Carcinogenic by RTECS criteria. Liver- Tumors. DEVELOPMENTAL TOXICITY: REPRODUCTIVE EFFECTS: Tetrahydrofuran: Toxic Effects: Rat TCLo (inhalation) 5000ppm/6 Hours, female, 6-19 Days of pregnancy. Effects on Embryo or Fetus- Fetotoxicity. Mouse TCLo (inhalation) 1800ppm/6 Hours, female, 6-17 Days of pregnancy. Toxic Effects: Effects on Fertility- Post-implantation mortality. Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection. (ca. 1.0mol/L THF Soln.) Section IV.