Hydrazine, Anhydrous

Potential Acute Health Effects

Corrosive to skin, eyes, and respiratory system. Liquid or spray mist may produce tissue damage, particularly in mucous membranes of the eyes, mouth and respiratory tract. Skin contact may produce burns. Eye contact can result in corneal damage or blindness. Inhalation of the spray mist may produce severe irritation of respiratory tract, characterized by coughing, choking, or shortness of breath. Corrosive materials may cause serious injury if ingested. Toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness or death. Skin contact may result in sensitization. Always cover all exposed skin with an impermeable layer and use proper eye protection. A OSHA/MSHA approved dust and vapor respirator is required when working with this material. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

Potential chronic health

CARCINOGENIC EFFECTS : Carcinogenic by RTECS criteria. MUTAGENIC EFFECTS : Not available.

Teratogenic Effects

Tumorigenic Effects Rat TCLo Inhalation 5ppm/6 hours/1 year intermittent TOXIC Effects: Tumorigenic - Carcinogenic by RTECS criteria Endocrine - Thyroid tumors Rat TDLo Oral 900 mg/kg/2 years continuous TOXIC Effects: Tumorigenic - Neoplastic by RTECS criteria Liver - Tumors Mouse TDLo Intraperitoneal 400 mg/kg/ 5 weeks intermittent TOXIC Effects: Tumorigenic - Carcinogenic by RTECS criteria Blood - Tumors Bood - Leukemia DEVELOPMENTAL TOXICITY: Reproductive Effects. Rat TDLo Intraperitoneal 30 mg/kg, female 7-9 days of pregnancy TOXIC Effects: Specific Developmental Abnormalities - Central nervous system Specific Developmental Abnormalities - Musculoskeletal system Specific Developmental Abnormalities - Urogenital system Rat TDLo Subcutaneous 80 mg/kg, female 11-20 days of pregnancy TOXIC Effects: Effects on Embryo or Fetus - Fetotoxicity Effects on Embryo or Fetus - Fetal death Effects on Newborn - Viability index Hamster TCLo Inhalation 1ppm/6 hours, male 1 year prior to mating TOXIC Effects: Paternal Effects - Testes, epididymis, sperm duct Repeated or prolonged contact with spray mist may produce chronic eye irritation and severe skin irritation. Repeated or prolonged exposure to spray mist may produce respiratory tract irritation leading to frequent attacks of bronchial infection. Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. Section IV.