Hexachlorobenzene

Potential Acute Health Effects

Toxic if ingested or inhaled. Avoid prolonged contact with this material. Overexposure may result in serious illness or death. Causes photosensitivity. Exposure to light can result in allergic reactions resulting in dermatologic lesions, which can vary from sunburn-like responses to edematous, vesiculated lesions or bullae. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.

Potential chronic health

CARCINOGENIC EFFECTS - Not available. MUTAGENIC EFFECTS _ Not available.

Teratogenic Effects

Tumorigenic Effects. Rat TD Oral 5475 mg/kg/2 years continuous. TOXIC Effects: Tumorigenic — Carcinogenic by RTECS criteria. Liver - Tumors. Kidney, Ureter, and Bladder - Kidney tumors. Rat TDLo Oral 2738 mg/kg/2 years continuous. TOXIC Effects: Tumorigenic — Carcinogenic by RTECS criteria. Kidney, Ureter, and Bladder - Kidney tumors. Blood - Leukemia. Mouse TDLo Oral 6972 mg/kg/83 weeks continuous. TOXIC Effects: Tumorigenic — Neoplastic by RTECS criteria. Liver - Tumors. Blood - Lymphomas including Hodgkin's disease. DEVELOPMENTAL TOXICITY Reproductive Effects. Rat TDLo Oral 6450 mg/kg female 1-22 days of pregnancy and 21 days after birth. TOXIC Effects: Specific Developmental Abnormalities - Blood and lymphatic system. Specific Developmental Abnormalities - Immune and reticuloendothelial system. Rat TDLo Oral 40 mg/kg female 10-13 days of pregnancy. TOXIC Effects: Specific Developmental Abnormalities - Musculoskeletal system. Mouse TDLo Oral 600 mg/kg female 6-17 days of pregnancy. TOXIC Effects: Effects on Newborn - Weaning or lactation index. Effects on Newborn - Biochemical and metabolic. Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. Continued on Next Page Printed 2/28/2007. Emergency phone number