General Information
Revision date
2011-12-20
Product name
Estrone
Product Synonyms
Estra-1,3,5(10)-trien-17-one, 3-hydroxy- (CA INDEX
Chemical name
Estrone
CAS No.
53-16-7
supplier name
TCI America
Icons in SDS
Company Information
company name
TCI America
Section 2
Potential Acute Health Effects
Harmful if ingested or inhaled. Minimize exposure to this material. Severe overexposure can result in injury or death. Follow safe industrial hygiene practices and always wear proper protective equipment when handling this compound.
Potential chronic health
CARCINOGENIC EFFECTS : Equivocal tumorigenic agent by RTECS criteria MUTAGENIC EFFECTS : Not available.
Teratogenic Effects
Tumorigenic Effects Rat TDLo (implant) 16 mg/kg; female Toxic Effects: Tumorigenic - Equivocal tumorigenic agent by RTECS criteria Skin and Appendages - Tumors Mouse TDLo (parenteral) 1200 ug/kg/1 week intermittent; female Toxic Effects: Tumorigenic - Equivocal tumorigenic agent by RTECS criteria Skin and Appendages - Tumors Guinea Pig TDLo (subcutaneous) 40 mg/kg/18 weeks intermittent; female Toxic Effects: Tumorigenic - Equivocal tumorigenic agent by RTECS criteria Tumorigenic Effects - Uterine tumors DEVELOPMENTAL TOXICITY: Reproductive Effects: Man TDLo (Implant) 1586 ug/kg; male 60 days prior to mating Toxic Effects: Paternal Effects - Spermatogenesis Rat TDLo (parenteral) 25 ug/kg; female 2 days of pregnancy Toxic Effects: Effects on Fertility - Litter size Effects on Fertility - Other measures of fertility Rabbit TDLo (Subcutaneous) 6 ug/kg; female 1-3 days of pregnancy Toxic Effects: Effects on Fertility - Pre-implantation mortality Repeated or prolonged exposure to this compound is not known to aggravate existing medical conditions. Section IV.
