ALSAN RS 223 POWDER

SECTION 2: Hazards identification

DANGER May cause cancer. Causes damage to organs through prolonged or repeated exposure. May cause respiratory irritation. Causes eye irritation. Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not eat, drink or smoke using this product. Do not breathe dust. Use only outdoors or in a well-ventilated area. Wash hands thoroughly after handling. Wear protective gloves, eye protection and a dust mask. Store locked up. Dispose of container in accordance with local, regional and national regulations. SECTION III: COMPOSITION AND INFORMATION ON DANGEROUS INGREDIENTS NAME CAS # % WEIGHT EXPOSURE LIMIT (ACGIH) TLV-TWA TLV-STEL Silica, Quartz 14808-60-7 60-100 0.025 mg/m3 Not available Ferric oxide 1309-37-1 0.1-1 5 mg/m3 Not available Effects of Short-Term (Acute) Exposure Effects of Long-Term (Chronic) Exposure INHALATION RESPIRATORY EFFECTS Silica, Quartz: In general, high concentrations of dust may cause Silica, Quartz: The respiratory effects from long-term exposure to fine, coughing and mild, temporary irritation following a short-term airborne crystalline silica dust are well documented. Occupational exposure. No human or relevant animal information was located. exposures have been associated with the development of silicosis, Quartz can have potentially serious respiratory effects following long- pulmonary tuberculosis and other diseases of the respiratory system. term inhalation. (1) Silicosis is a progressive, chronic, disabling lung disease. The early symptoms of silicosis (cough, mucous production and shortness of Ferric oxide: No information available. (1) breath upon exertion) are not specific to this disease. So, the SKIN CONTACT development of silicosis may not be detected until advanced stages of Silica, Quartz: In general, quartz is not expected to be irritating to the the disease. Silicosis may continue to develop even after exposure to skin. No human or animal information was located. Quartz is not crystalline silica has stopped. Evidence of silicosis can normally be expected to be absorbed through the skin. (1) seen on a chest x- ray. The risk of developing silicosis and the severity of silicosis depend on the airborne concentration of respirable-size Ferric oxide: No information available. (1) crystalline silica dust to which an employee is exposed and the duration EYE CONTACT of exposure. Particles with diameters less than 1 micron and freshly Silica, Quartz: In general, quartz is not expected to be irritating except cleaved particles (for example, those produced by sandblasting) are as a "foreign object". Some tearing, blinking and mild temporary pain considered the most hazardous. There are 3 types of silicosis which a may occur as the solid material is rinsed from the eye by tears. No worker may develop based on the duration of exposure and the relevant human or animal information was located. (1) exposure concentration. "Chronic" or "classic" silicosis is the most common and results from exposures for 10 or more years to relatively Ferric oxide: No information available. (1) low concentrations. In cases of mild silicosis, there is typically no INGESTION significant respiratory impairment, although there is x-ray evidence of Silica, Quartz: Quartz is not expected to be harmful if ingested. No lung injury. In severe cases, significant and increasingly severe human or reliable animal information was located. Ingestion is not a respiratory impairment develops. There is no effective treatment for the typical route of occupational exposure. (1) disease. Life expectancy may be reduced, depending on the severity of the case. Death is not usually a direct result of silicosis, but heart failure Ferric oxide: No information available. (1) (cor pulmonale) may occur as the heart has increasing difficulty pumping blood through the scarred lungs. Silicosis may be complicated by the development of bacterial infections, including tuberculosis. "Accelerated" silicosis results from exposure to high concentrations of crystalline silica over a period of 5-10 years. The disease continues to develop even after exposure stops, and is often associated with TERATOGENICITY, EMBRYOTOXICITY, FETOTOXICITY autoimmune diseases for example, scleroderma (a disease involving Silica, Quartz: Quartz is not known to cause developmental toxicity. thickening of the skin). "Acute" silicosis (also referred to as "silicotic No human or animal information was located. (1) alveolar proteinosis") is rare, but develops from exposure to very high Ferric oxide: No information available. (1) concentrations. Symptoms may occur within a few weeks to 4-5 years REPRODUCTIVE TOXICITY after the first exposure. Death often results within a few years. Acute Silica, Quartz: Quartz is not known to cause reproductive toxicity. No silicosis has occurred in occupations such as sandblasting or tunneling human or animal information was located. (1) where exposure controls were minimal. Occupational exposures to respirable crystalline silica have also been associated with chronic Ferric oxide: No information available. (1) obstructive pulmonary disease, including bronchitis and emphysema, MUTAGENICITY independent of silicosis. (1) Silica, Quartz: The available evidence is not adequate to conclude that Ferric oxide: No information available. (1) quartz is a mutagen. No conclusions can be drawn from the human information located. A positive result was obtained in a non-standard RESPIRATORY SENSITIZATION study using live rats. Positive and negative results were obtained in Silica, Quartz: Quartz is not known to cause respiratory sensitization. studies using live animals exposed by routes which are not relevant to No human or animal information was located. (1) occupational exposures. Positive and negative results were obtained in Ferric oxide: No information available. (1) cultured mammalian cells, while a negative result was obtained in a study in bacteria. (1) SKIN Silica, Quartz: Foreign-body reactions (granulomas) have been Ferric oxide: No information available. (1) observed after crystalline silica has accidentally gotten lodged under TOXICOLOGICALLY SYNERGISTIC MATERIALS the skin, as the result of a physical injury. Often this effect is delayed Silica, Quartz: There is disagreement about whether tobacco smoke for weeks to years. (1) increases the severity of the effect of crystalline silica on respiratory Ferric oxide: No information available. (1) impairment. Simultaneous exposure to known carcinogens, for example, benzo(a)pyrene, can increase the carcinogenicity of SKIN SENSITIZATION crystalline silica. (1) Silica, Quartz: Quartz is not known to cause skin sensitization. No human or animal information was located. (1) Ferric oxide: No information available. (1) POTENTIAL FOR ACCUMULATION Silica, Quartz: Quartz dust can accumulate in the lungs. Inhaled KIDNEY/URINARY SYSTEM particles are deposited at various locations within the respiratory tract, Silica, Quartz: Several human population studies have found depending on their shape, mass, aerodynamic characteristics and other significant associations between the inhalation exposure to airborne physical properties. Respirable particles are considered to be those with crystalline silica and kidney diseases. However, there is not enough an aerodynamic diameter of less than 5 microns. These particles can evidence to conclude a causal link. (1) deposit in the alveolar spaces in the lungs, are cleared more slowly and Ferric oxide: No information available. (1) are more likely to cause injury. Particles larger than 5 microns are more likely to be deposited in the tracheobronchial airways where they are LIVER cleared more quickly. Most, but not all, crystalline silica is cleared Silica, Quartz: There have been reports of harmful liver effects in from the lungs after inhalation and deposition. The elimination of workers exposed to crystalline silica caused by deposits of silica quartz particles continues for many years after the last exposure. Silica particles. However, these effects have not been studied in depth. (1) is slightly absorbed into the body. Absorbed silica is deposited mainly Ferric oxide: No information available. (1) in the liver, spleen and regional lymph nodes. Silicic acid absorbed into the blood stream is excreted through the kidneys. (1) IMMUNE SYSTEM Silica, Quartz: There have been many published case reports that Ferric oxide: No information available. (1) describe various autoimmune disorders in workers exposed to crystalline silica. These disorders include scleroderma (a disease