ALSAN 610 PART A

Potential health effects

tert-Butyl acetate: The liquid may be a mild to moderate skin irritant, based on Effects of Short-Term (Acute) Exposure comparison to related butyl acetates. There is no human or animal INHALATION information available for tert-butyl acetate. (1) Castor oil: Alkoxylated ethylene diamine: Castor oil does not form a vapour at room temperature. Therefore, it Slightly irritating to skin. (2) must be heated or misted before inhalation exposure would occur. following inhalation exposure are not expected, due to EYE CONTACT the overall low toxicity of castor oil. There is no human or animal Castor oil: information available. (1) Castor oil is not irritating or a mild irritant, based on animal information. It is sometimes used as an eye ointment. (1) tert-Butyl acetate: The vapour is probably irritating to the nose and throat. Exposures to tert-Butyl acetate: high concentrations can probably cause signs of central nervous system The liquid can probably cause moderate to severe eye irritation, based depression including headache, dizziness, nausea and unconsciousness. on comparison to related acetates. The vapour can probably cause mild There is no specific information available for tert-butyl acetate, but to severe eye irritation, depending on the concentration. There is no effects would probably be like those observed in animals and humans specific information available for tert-butyl acetate. (1) following exposure to other butyl acetates. (1) Alkoxylated ethylene diamine: Slightly irritating to eyes. (2) No know significant effects or critical hazards. (2) INGESTION SKIN CONTACT Castor oil: Castor oil is not expected to produce significant harmful effects if Castor oil is not irritating or a mild irritant, based on animal and human accidentally ingested, based on animal toxicity information and information. Application of 50 mL of castor oil, under a patch for 48 experience gained through the use of castor oil as a laxative in humans. hours, was mildly irritating to humans. Castor oil is not expected to A single oral dose is considered safe. Ingestion of large doses can cause produce harmful effects if absorbed through the skin. (1) nausea, vomiting, stomach cramps and diarrhoea. Ingestion is not a typical route of occupational exposure. (1) tert-Butyl acetate: Alkoxylated ethylene diamine: Related butyl acetates are not very toxic by ingestion. Like other butyl No significant effects or critical hazards. (2) acetates, tert-butyl acetate may be irritating to the mouth and throat. Ingestion of large amounts may produce signs of CNS depression, like TOXICOLOGICALLY SYNERGISTIC MATERIALS those described for "Inhalation" above. Ingestion is not a typical route Castor oil: No information is available. (1) of occupational exposure. (1) tert-Butyl acetate: Alkoxylated ethylene diamine: No information is available. (1) Slightly hazardous in case of ingestion. (2) Alkoxylated ethylene diamine: Effects of Long-Term (Chronic) Exposure No significant effects or critical hazards. (2) SKIN SESITIZATION POTENTIAL FOR ACCUMULATION Castor oil: There is insufficient information available to determine if castor oil is Does not accumulate. (1) an occupational sensitizer. There are several case reports of dermatitis tert-Butyl acetate: and occasional facial swelling from the use of lipsticks, where castor Probably does not accumulate. Studies suggest that tert-butyl acetate is oil is believed to be the cause. There is no animal information rapidly broken down in the body to acetic acid and tert-butanol and available. (1) eliminated in the urine. Another study shows that tert-butyl acetate is tert-Butyl acetate: more slowly eliminated from blood than n-butyl acetate. (1) No information available. (1) Alkoxylated ethylene diamine: No significant effects or critical hazards. (2) CARCINOGENICITY