SPI-980

Potential Acute Health Effects

Powder/dust eye irritation is a physical, not a chemical effect. Solid particles on the eye (powder/dust) may cause pain and be accompanied by irritation. Dust inhalation may cause coughing, mucous production and shortness of breath.

Potential chronic health

Contact dermatitis may occur in individuals under extreme conditions of prolonged and repeated contact, high exposure and temperature, and occlusion (held onto the skin) by clothing. No evidence of adverse lung effects from polyacrylate dust exposure was observed in studies of workers. Neither lower airway symptoms, chronic parenchymal disease, radiographic changes, nor clinically important effects on lung function were found to result from polyacrylate exposure. Only a small increase in upper respiratory symptoms appeared to be related to exposure. However, various lung effects such as inflammation, hyperplasia (abnormal increases in the number of cells composing a tissue or organ), scarring (fibrosis), changes in the air sac (alveolar) ducts of the lung, and tumors were noted in laboratory studies with rodents inhaling concentrations of a water absorbent sodium polyacrylate dust greater than 0.05 mg/m3 for the majority of www.siliconesplus.com | info@siliconesplus.com | 817-469-7777 1 their lives. Furthermore, some lung or lung cell effects were found in rodent laboratory studies of shorter duration. Signs/Symptoms of Exposure: Irritation Routes of Exposure/Entry: Skin Contact, Inhalation, Ingestion, Eye Contact Target Organs: Respiratory System, Skin

Medical Conditions Generally Aggravated by Exposure

Pre-existing skin problems may be aggravated by prolonged or by exposure: repeated contact. Pre-existing respiratory disease(s) may be aggravated by prolonged or repeated inhalation of airborne dust. Carcinogenic status: Not listed or regulated by IARC, NTP, OSHA, or ACGIH.