SPI-950

CLP CLASSIFICATION

This substance is not classified in the Annex I of Directive 67/548/EEC and REGULATION (EC) No 1272/2008. Acute health effects: Powder/dust eye irritation is a physical, not a chemical effect. Solid particles on the eye (powder/dust) may cause pain and be accompanied by irritation. Dust inhalation may cause coughing, mucous production and shortness of breath.

Potential chronic health

Contact dermatitis may occur in individuals under extreme conditions of prolonged and repeated contact, high exposure and temperature, and occlusion (held onto the skin) by clothing. No evidence of adverse lung effects from polyacrylate dust exposure was observed in studies of workers. Neither lower airway symptoms, chronic parenchymal disease, radiographic changes, nor clinically important effects on lung function were found to result from polyacrylate exposure. Only a small increase in upper respiratory symptoms appeared to be related to exposure. However, various lung effects such as inflammation, hyperplasia (abnormal increases in the number of cells composing a tissue or organ), scarring (fibrosis), changes in the air sac (alveolar) ducts of the lung, and tumors were noted in laboratory studies with rodents inhaling concentrations of a water absorbent sodium polyacrylate dust greater than 0.05 mg/m3 for the majority of their lives. Furthermore, some lung or lung cell effects were found in rodent laboratory studies of shorter duration.