Capping Reagent A, Tetrahydrofuran

Sigma-Aldrich Pte Ltd

Revision date : 2022-05-11

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GHS06 GHS02 GHS08 GHS05
Health risk rating 4
Safety risk rating 3
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

203-726-8/109-99-9

Name of the chemical

Tetrahydrofuran (618/2012)

Concentration

>=70-<90

EC/CAS

203-564-8/108-24-7

Name of the chemical

acetic anhydride

Concentration

>=10-<20

EC/CAS

203-809-9/110-86-1

Name of the chemical

Pyridine

Concentration

>=10-<20

Listed in

General Information

Version

8.7

Revision date

2022-05-11

Product name

Capping Reagent A, Tetrahydrofuran

1.2.1 Relevant identified uses

Peptide synthesis

Emergency telephone

+65 6890 6633, +65 6890 6639, 1-800-262-8200

Icons in SDS

GHS02 GHS05 GHS06 GHS08

Company Information

company name

Sigma-Aldrich Pte Ltd

e-mail address of the competent person responsible for the Safety Data Sheet

TechnicalService@merckgroup.com

GHS Information

Signal word

none

Hazard Codes

Hazard statements (CLP)

H225, H302, H315, H318, H331, H335, H336, H351

Hazard statements

Code

Statements

H225

Highly Flammable liquid and vapour

Section 2

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Flammable liquids (Category 2), H225 Acute toxicity, Oral (Category 4), H302 Acute toxicity, Inhalation (Category 3), H331 Skin corrosion/irritation (Category 2), H315 Serious eye damage/eye irritation (Category 1), H318 Carcinogenicity (Category 2), H351 Specific target organ toxicity - single exposure (Category 3), Respiratory system, Central nervous system, H335, H336 For the full text of the H-Statements mentioned in this Section, see Section 16.

Signal word

Danger none

Hazard statements

H225 Highly flammable liquid and vapor. H302 Harmful if swallowed. H315 Causes skin irritation. H318 Causes serious eye damage. H331 Toxic if inhaled. H335 May cause respiratory irritation. H336 May cause drowsiness or dizziness. H351 Suspected of causing cancer. none

Prevention

P201 Obtain special instructions before use. P210 Keep away from heat/ sparks/ open flames/ hot surfaces. No smoking. P233 Keep container tightly closed. P261 Avoid breathing mist or vapors. P264 Wash skin thoroughly after handling. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection.

Response

P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower. P305 + P351 + P338 + IF IN EYES: Rinse cautiously with water for several minutes. P310 Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/ doctor. P370 + P378 In case of fire: Use dry sand, dry chemical or alcohol-resistant foam to extinguish.

Storage

P403 + P233 Store in a well-ventilated place. Keep container tightly closed. Reduced Labeling (<= 125 ml)

Precautionary statements

none Refer to the Safety Data Sheet before use.

Other hazards

May form explosive peroxides

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