LentiBrite RFP-Vimentin Lentiviral Biosensor

SECTION 2: Hazards identification

Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008. Classification of the substance or mixture

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher. Biohazard, Biosafety Level 2, Lentiviruses are a subset of retroviruses, with the ability to integrate into host chromosomes, and to infect non-dividing cells. These viruses can cause severe immunologic and neurologic disease in their natural hosts. Lentivirus vector systems can include viruses of non-human/non-primate origin . The more recent generation vectors have been designed to significantly diminish the possibility for recombination to occur resulting in a wild type- potentially infectious virus. Typical lentivirus vectors are packaged using pseudotyped enveloped proteins. It is usually recommended that work with nonhuman lentiviruses that are incapable of establishing productive infections in humans be conducted at BSL-2. Work with simian or human lentiviruses is typically conducted at a higher containment level. genetically modified organism

2.1 Classification of the substance or mixture

Not a hazardous substance or mixture according to Regulation (EC) No 1272/2008.