Lapatinib

Hazard statements (CLP)

H361d, H362, H373, H413

Code

Statements

H361d

Suspected of damaging the unborn child

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

Signal word

Warning Warning

Hazard statements

H361d Suspected of damaging the unborn child. H362 May cause harm to breast-fed children. H373 May cause damage to organs (Liver) through prolonged or repeated exposure. H413 May cause long lasting harmful effects to aquatic life. H362 May cause harm to breast-fed children. H413 May cause long lasting harmful effects to aquatic life. H361d Suspected of damaging the unborn child.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P260 Do not breathe dust. P263 Avoid contact during pregnancy and while nursing. P264 Wash skin thoroughly after handling. P273 Avoid release to the environment. P202 Do not handle until all safety precautions have been read and understood. P308 + P313 IF exposed or concerned: Get medical advice/ attention.

Response

P308 + P313 IF exposed or concerned: Get medical advice/ attention. Reduced Labelling (<= 125 ml)

Supplemental label elements

none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Classification (REGULATION (EC) No 1272/2008) Reproductive toxicity, Category 2 H361d: Suspected of damaging the unborn child. Effects on or via lactation H362: May cause harm to breast-fed children. Specific target organ toxicity - H373: May cause damage to organs through repeated exposure, Category 2, prolonged or repeated exposure. Liver Long-term (chronic) aquatic hazard, H413: May cause long lasting harmful effects Category 4 to aquatic life.