Crizotinib

Sigma-Aldrich Chemie GmbH

Revision date : 2023-02-11

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GHS07 GHS08 GHS09
Health risk rating 4
Safety risk rating 1
Environmental risk rating 4

General Information

Version

6.6

Revision date

2023-02-11

Product name

Crizotinib

CAS No.

877399-52-5

REACH No

is

Emergency telephone

+49 (0)696 43508409

Icons in SDS

GHS07 GHS08 GHS09

Company Information

company name

Sigma-Aldrich Chemie GmbH

e-mail address of the competent person responsible for the Safety Data Sheet

technischerservice@merckgroup.com

GHS Information

Signal word

Warning

Hazard Codes

Hazard statements (CLP)

H317, H319, H341, H400

Hazard statements

Code

Statements

H317

May cause an allergic skin reaction

Section 2

SECTION 2: Hazards identification

2.1 Classification of the substance or mixture

Classification

2.2 Label elements

Labelling

Signal word

Warning Warning

Hazard statements

H317 May cause an allergic skin reaction. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H400 Very toxic to aquatic life. Reduced Labeling (<= 125 ml) H317 May cause an allergic skin reaction. H341 Suspected of causing genetic defects.

Precautionary statements

P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P308 + P313 IF exposed or concerned: Get medical advice/ attention. P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P302 + P352 IF ON SKIN: Wash with plenty of water. P308 + P313 IF exposed or concerned: Get medical advice/ attention.

Supplemental label elements

none none

2.3 Other hazards

This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

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