General Information
Version
8.3
Revision date
2023-12-30
Product name
RNA isolation kit
REACH No
This
Emergency telephone
+41 43-508-2011, +41 44-251-5151
Icons in SDS
Company Information
company name
Sigma-Aldrich Chemie GmbH
e-mail address of the competent person responsible for the Safety Data Sheet
technischerservice@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H225, H301, H301+H331, H310, H314, H317, H318, H331, H336, H341, H351, H361d, H372, H373, H400, H410, H411
Hazard statements
Code
Statements
H225
Highly Flammable liquid and vapour
Section 2
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Flammable liquids, (Category 2) H225: Highly flammable liquid and vapor. Acute toxicity, (Category 3) H301: Toxic if swallowed. Acute toxicity, (Category 3) H331: Toxic if inhaled. Acute toxicity, (Category 2) H310: Fatal in contact with skin. Skin corrosion, (Sub-category H314: Causes severe skin burns and eye 1B) damage. Serious eye damage, (Category H318: Causes serious eye damage. 1) Skin sensitization, (Category 1) H317: May cause an allergic skin reaction. Germ cell mutagenicity, H341: Suspected of causing genetic (Category 2) defects. Carcinogenicity, (Category 2) H351: Suspected of causing cancer. Reproductive toxicity, (Category H361d: Suspected of damaging the unborn 2) child. Specific target organ toxicity - H336: May cause drowsiness or dizziness. single exposure, (Category 3), Central nervous system Specific target organ toxicity - H372: Causes damage to organs through repeated exposure, (Category 1), prolonged or repeated exposure if Liver, Kidney swallowed. Specific target organ toxicity - H373: May cause damage to organs repeated exposure, (Category 2), through prolonged or repeated exposure. Nervous system, Kidney, Liver, Skin Specific target organ toxicity - H373: May cause damage to organs repeated exposure, (Category 2), through prolonged or repeated exposure if Heart swallowed. Short-term (acute) aquatic H400: Very toxic to aquatic life. hazard, (Category 1) Long-term (chronic) aquatic H411: Toxic to aquatic life with long lasting hazard, (Category 2) effects.
2.2 Label elements
Labelling
Signal word
Danger Danger
Hazard statements
H225 Highly flammable liquid and vapor. H301 + H331 Toxic if swallowed or if inhaled. H310 Fatal in contact with skin. H314 Causes severe skin burns and eye damage. H317 May cause an allergic skin reaction. H336 May cause drowsiness or dizziness. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H361d Suspected of damaging the unborn child. H372 Causes damage to organs (Liver, Kidney) through prolonged or repeated exposure if swallowed. H373 May cause damage to organs (Nervous system, Kidney, Liver, Skin) through prolonged or repeated exposure. H373 May cause damage to organs (Heart) through prolonged or repeated exposure if swallowed. H410 Very toxic to aquatic life with long lasting effects. H310 Fatal in contact with skin. H317 May cause an allergic skin reaction. H341 Suspected of causing genetic defects. H351 Suspected of causing cancer. H372 Causes damage to organs through prolonged or repeated exposure if swallowed. H314 Causes severe skin burns and eye damage. H361d Suspected of damaging the unborn child. H301 + H331 Toxic if swallowed or if inhaled.
Precautionary statements
P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P303 + P361 + P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water. P304 + P340 + P310 IF INHALED: Remove person to fresh air and keep comfortable for breathing. Immediately call a POISON CENTER/ doctor. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Supplemental label elements
EUH032 Contact with acids liberates very toxic gas. Reduced Labeling (<= 125 ml) EUH032 Contact with acids liberates very toxic gas.
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
ECOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.
TOXICOLOGICAL INFORMATION
The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.