N-(Hydroxymethyl)acrylamide solution

Sigma-Aldrich Chemie GmbH

Revision date : 2025-11-04

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GHS08 GHS06
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

213-103-2/924-42-5

Name of the chemical

N-(Hydroxymethyl)acrylamid; Methylolacrylamid; [NMA] (2020/1182)

Concentration

>=30-<50

EC/CAS

201-173-7/79-06-1

Name of the chemical

Acrylamide

Concentration

>=3-<10

EC/CAS

200-001-8/50-00-0

Name of the chemical

Formaldehyde

Concentration

>=1-<3%

General Information

Version

8.1

Revision date

2025-11-04

Product name

N-(Hydroxymethyl)acrylamide solution

REACH No

This

Emergency telephone

+49 (0)696 43508409

Icons in SDS

GHS06 GHS08

Company Information

company name

Sigma-Aldrich Chemie GmbH

e-mail address of the competent person responsible for the Safety Data Sheet

technischerservice@merckgroup.com

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H301, H317, H340, H350, H361, H372, H373

Hazard statements

Code

Statements

H301

Toxic if swallowed

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture Acute toxicity, (Category 3) H301: Toxic if swallowed Skin sensitisation, (Category 1) H317: May cause an allergic skin reaction Germ cell mutagenicity, H340: May cause genetic defects Category 1B) Carcinogenicity, (Category 1B) H350: May cause cancer Reproductive toxicity, (Category H361: Suspected of damaging fertility or the unborn child Specific target organ toxicity - H372: Causes damage to organs through repeated exposure, (Category 1) prolonged or repeated exposure Specific target organ toxicity - H373: May cause damage to organs repeated exposure, (Category 2), through prolonged or repeated exposure if Peripheral nervous system swallowed Persistent, bioaccumulative and EUH440: Accumulates in the environment toxic and living organisms including in humans Very persistent and very EUH441: Strongly accumulates in the bioaccumulative environment and living organisms including in humans

Signal word

Danger Danger

Hazard statements

H301 Toxic if swallowed. H317 May cause an allergic skin reaction. H340 May cause genetic defects. H350 May cause cancer. H361 Suspected of damaging fertility or the unborn child. H372 Causes damage to organs through prolonged or repeated exposure. H373 May cause damage to organs (Peripheral nervous system) through prolonged or repeated exposure if swallowed. EUH441 Strongly accumulates in the environment and living organisms including in humans. Restricted to professional users. Reduced Labelling (<= 125 ml) H301 Toxic if swallowed. H317 May cause an allergic skin reaction. H340 May cause genetic defects. H350 May cause cancer. H361 Suspected of damaging fertility or the unborn child. H372 Causes damage to organs through prolonged or repeated exposure. EUH441 Strongly accumulates in the environment and living organisms including in humans.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P391 Collect spillage. P501 Dispose of contents/ container to an approved waste disposal plant. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. P280 Wear protective gloves/ protective clothing/ eye protection/ face protection. P301 + P310 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. P391 Collect spillage. P501 Dispose of contents/ container to an approved waste disposal plant.

Supplemental label elements

none none

2.3 Other hazards

This substance/mixture contains components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB).

ECOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

TOXICOLOGICAL INFORMATION

The substance/mixture does not contain components considered to have endocrine disrupting properties according to REACH Article 57(f) or Commission Delegated regulation (EU) 2017/2100 or Commission Regulation (EU) 2018/605 at levels of 0.1% or higher.

2.1 Classification of the substance or mixture

Acute toxicity, (Category 3) H301: Toxic if swallowed. Skin sensitisation, (Category 1) H317: May cause an allergic skin reaction. Germ cell mutagenicity, H340: May cause genetic defects. (Category 1B) Carcinogenicity, (Category 1B) H350: May cause cancer. Reproductive toxicity, (Category H361: Suspected of damaging fertility or 2) the unborn child. Specific target organ toxicity - H372: Causes damage to organs through repeated exposure, (Category 1) prolonged or repeated exposure. Specific target organ toxicity - H373: May cause damage to organs repeated exposure, (Category 2), through prolonged or repeated exposure if Peripheral nervous system swallowed. Persistent, bioaccumulative and EUH440: Accumulates in the environment toxic and living organisms including in humans. Very persistent and very EUH441: Strongly accumulates in the bioaccumulative environment and living organisms including in humans.

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