Note: Ingredients listed on restricted chemical lists
EC/CAS
200-413-8
Name of the chemical
Methotrexate (INN)
Concentration
<= 100 %
General Information
Revision date
2023-04-22
Product name
Methotrexate
CAS No.
59-05-2
REACH No
is
Emergency telephone
0800 181 7059 (CHEMTREC Deutschland
Icons in SDS
Company Information
company name
Sigma-Aldrich Chemie GmbH
e-mail address of the competent person responsible for the Safety Data Sheet
technischerservice@merckgroup.com
GHS Information
Signal word
Danger
Hazard Codes
Hazard statements (CLP)
H301, H315, H319, H341, H360D
Hazard statements
Code
Statements
H301
Toxic if swallowed
Section 2
CLP CLASSIFICATION
Acute toxicity, Oral (Category 3), H301 Skin irritation (Category 2), H315 Eye irritation (Category 2), H319 Germ cell mutagenicity (Category 2), H341 Reproductive toxicity (Category 1B), H360D For the full text of the H-Statements mentioned in this Section, see Section 16.
2.2 Label elements
Labelling according Regulation (EC) No 1272/2008
Signal word
Danger Danger
Hazard statements
H301 Toxic if swallowed. H315 Causes skin irritation. H319 Causes serious eye irritation. H341 Suspected of causing genetic defects. H360D May damage the unborn child. Reduced Labeling (<= 125 ml) H301 Toxic if swallowed. H341 Suspected of causing genetic defects. H360D May damage the unborn child.
Precautionary statements
P201 Obtain special instructions before use. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth. P302 + P352 IF ON SKIN: Wash with plenty of water. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P201 Obtain special instructions before use. P301 + P310 + P330 IF SWALLOWED: Immediately call a POISON CENTER/ doctor. Rinse mouth.
Supplemental label elements
none none
2.3 Other hazards
This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vPvB) at levels of 0.1% or higher.
