Colchicine

Potential Acute Health Effects

Extremely hazardous in case of skin contact (corrosive, irritant, sensitizer, permeator), of eye contact (irritant), of ingestion, of inhalation. The amount of tissue damage depends on length of contact. Eye contact can result in corneal damage or blindness. Skin contact can produce inflammation and blistering. Inhalation of dust will produce irritation to gastro-intestinal or respiratory tract, characterized by burning, sneezing and coughing. Severe over-exposure can produce lung damage, choking, unconsciousness or death. Inflammation of the eye is characterized by redness, watering, and itching. Skin inflammation is characterized by itching, scaling, reddening, or, occasionally, blistering.

Potential chronic health

Effects Extremely hazardous in case of skin contact (corrosive, irritant, sensitizer, permeator), of eye contact (irritant), of ingestion, of inhalation. CARCINOGENIC EFFECTS Not available. MUTAGENIC EFFECTS Not available. TERATOGENIC EFFECTS Not available. DEVELOPMENTAL TOXICITY: PROVEN The substance is toxic to blood, kidneys, lungs, the nervous system, the reproductive system, liver, mucous membranes. Repeated or prolonged exposure to the substance can produce target organs damage. Repeated exposure of the eyes to a low level of dust can produce eye irritation. Repeated skin exposure can produce local skin destruction, or dermatitis. Repeated inhalation of dust can produce varying degree of respiratory irritation or p. 1 lung damage. Repeated exposure to an highly toxic material may produce general deterioration of health by an accumulation in one or many human organs. Repeated or prolonged inhalation of dust may lead to chronic respiratory irritation.