Δ9-Tetrahydrocannabinol

Hazard statements (CLP)

H302, H361, H413

Code

Statements

H302

Harmful if swallowed

SECTION 2: Hazards identification

Classification of the substance or mixture Acute oral toxicity: Category 4 Reproductive toxicity: Category 2 Aquatic chronic toxicity: Category 4

Signal word

Warning

Hazard statements

H302: Toxic if swallowed H361: Suspected of damaging fertility or the unborn child H413: May cause long lasting harmful effects to aquatic life

Prevention

P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P273: Avoid release to the environment. P280: Wear protective gloves.

Response

P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P312 If swallowed call a poison center or doctor/physician if you feel unwell. P304+P340 If inhaled Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well ventilated place. Keep container tightly closed. P405: Store locked up. P308+313 IF exposed or concerned Get medical advice

Disposal

P501: Dispose of content in accordance with national and local regulations.

2.3 Other hazards

Effects and Symptoms: May be harmful by inhalation. May cause drowsiness or dizziness. May affect the inflammatory response. To the best of our knowledge, the toxicological properties have not been thoroughly investigated.

2.1 Classification of the substance or mixture

Acute oral toxicity: Category 4 Reproductive toxicity: Category 2 Aquatic chronic toxicity: Category 4 2.2. Label elements GHS Signal word: Warning GHS Hazard statements: H302: Toxic if swallowed H361: Suspected of damaging fertility or the unborn child H413: May cause long lasting harmful effects to aquatic life GHS Precautionary statements: Prevention P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P264: Wash hands thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P273: Avoid release to the environment. P280: Wear protective gloves. Response P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P301+P312: If swallowed: call a poison center or doctor/physician if you feel unwell. P304+P340: If inhaled: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well ventilated place. Keep container tightly closed. P405: Store locked up. P308+313: IF exposed or concerned: Get medical advice. Disposal P501: Dispose of content in accordance with national and local regulations. 2.3. Other hazards Effects and Symptoms: May be harmful by inhalation. May cause drowsiness or dizziness. May affect the inflammatory response. To the best of our knowledge, the toxicological properties have not been thoroughly investigated. 3 SECTION 3: Composition/information on ingredients 3.1. Substances Common name: THC Other names: Dronabinol, Tetrahydrocannabinol CAS-No: 1972-08-3 RTECS: HP8225000 Impurities: not specified 3.2. Mixtures Not applicable. 4 SECTION 4: First aid measures 4.1. Description of first aid measures If inhaled: Move the person into fresh air. If not breathing, give artificial respiration and get immediate medical attention. In case of skin contact: Wash off with soap and plenty of water. Remove contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse. In case of eye contact: Hold eyelids apart and flush eyes with water. Have eyes examined and tested by medical personnel if any irritation occurs. If swallowed: Rinse mouth with water, provided the person is conscious. Never give anything by mouth to an unconscious person. Get medical attention if exposed to a great amount. Do NOT induce vomiting unless directed to do so by medical personnel. 4.2. Most important symptoms and effects, Drowsiness or wakefulness. May affect the inflammatory both acute and delayed response. If swallowed, the symptoms may occur one or more hours later. 4.3. Indication of any immediate medical Treat symptoms. No special immediate treatment required. attention and special treatment needed 5 SECTION 5: Firefighting measures 5.1. Extinguishing media Use water spray, alcohol-resistant foam, carbon dioxide or dry chemical spray. A solid water stream may be inefficient. 5.2. Special hazards arising from the May produce carbon oxides on combustion. substance or mixture 5.3. Advice for firefighters Keep containers cool with water spray. If necessary, wear self-contained breathing apparatus and full protective gear. 6 SECTION 6: Accidental release measure 6.1. Personal precautions, protective Wear gloves and other appropriate personal protection. equipment and emergency procedures 6.2. Environmental precautions Avoid release into the environment or drains. 6.3. Methods and material for containment Collect the spill mechanically. and cleaning up 6.4. Reference to other sections Information for safe handling see section 7. Information for personal protection see section 8. Information for disposal see section 13 7 SECTION 7: Handling and storage 7.1. Precautions for safe handling Avoid excessive exposure. 7.2. Conditions for safe storage, including any Keep protected from light and air at 15 – 25 °C. Avoid incompatibilities exposition to strong oxidizing agents. 7.3. Specific end use(s) No data available. 8 SECTION 8: Exposure controls / personal protection 8.1. Control parameters No data available. 8.2. Exposure controls Use process enclosures, local exhaust ventilation and general industrial hygiene practice. 8.3. Individual protection measures Eye protection: Safety glasses. Skin protection: Lab coat and protective gloves. Wash thoroughly with soap if contact occurs. Respiratory protection: No specific requirements. Thermal hazard: No specific requirements. 9 SECTION 9: Physical and chemical properties 9.1. Information on basic physical and Appearance: Almost colorless to light yellow, chemical properties sometimes faint purple on the surface or resinous mass. Odour: none pH: no data available Melting point: no data available Boiling point: 200 °C at 1 atm Flash point: no data available Evaporation rate: no data available Flammability: no data available Explosive limits: LEL: no data. UEL: no data Vapor pressure: no data available Vapor density: no data available Relative density: no data available Solubility: poor water soluble (0.0028 mg/mL at 23 ºC) Partition coefficient: not water soluble Autoignition point: no data available Decomposition temp.: no data available Viscosity: no data available 9.2. Other information Density: no data available Molecular formula: C21H30O2 Molecular weight: 314.46 g/mol Percent volatile: no data available 10 SECTION 10: Stability and reactivity 10.1. Reactivity No data available. 10.2. Chemical stability Stable at room temperature. Oxidation may occur. 10.3. Possibility of hazardous reactions: None. 10.4. Conditions to avoid Light, heat. 10.5. Incompatible materials Strong oxidizing agents. 10.6. Hazardous decomposition products No data available. 11 SECTION 11: Toxicological information 11.1. Information on toxicological effects Acute toxicity LD50 oral mouse: 482 mg/kg rat: 666 mg/kg dog: 3000 mg/kg monkey: 9000 mg/kg LD50 intravenous mouse: 42 mg/kg rat: 29 mg/kg Lowest toxic dose oral human: unknown Skin corrosion or irritation: Not classified as hazardous. Serious eye damage or irritation: Not classified as hazardous. Respiratory or skin sensitization: Not classified as hazardous. Germ cell mutagenicity: No data available. Carcinogenicity: Not confirmed human carcinogen. Reproductive toxicity: Suspected to damage fertility or the unborn child. TDLo oral mouse female: 110 mg/kg TDLo oral mouse male: 125 mg/kg Specific target organ toxicity Single exposure: Not classified as hazardous. Repeated exposure: Not classified as hazardous. Aspiration hazard: Not classified as hazardous. 11.2. Routes of exposure Ingestion: May affect mucosal inflammatory response. Inhalation: May affect mucosal inflammatory response. Skin: May affect skin inflammatory response. Eyes: May affect eye inflammatory response. 11.3. Symptoms of exposure Exposure may affect the inflammatory response and cause dizziness or wakefulness. To the best of our knowledge, the toxicological properties have not been fully investigated on humans. 11.4. Delayed and immediate effects No data available. 12 SECTION 12: Ecological information 12.1. Toxicity