Beuthanasia-D Solution

SECTION 2: Hazards identification

OSHA EMERGENCY OVERVIEW Clear, Pink Solution Odor unknown Toxic if swallowed. May be toxic by inhalation. May cause allergic reactions in susceptible individuals. Prolonged exposure may cause serious health effects. Causes effects to: - central nervous system - respiratory system - brain - cardiovascular system Causes birth defects. May cause effects to: - gastrointestinal tract - blood - immune system - liver - kidney Harmful to fish and aquatic organisms.

Potential health effects

The following summary is based upon available information about the individual ingredients of the mixture, or of the expected properties of the mixture. Only information about the ingredients that are expected to contribute significantly to the potential health hazard profile of the formulation(s) is presented. This product is intended to cause euthanasia in dogs upon administration intravenously. Euthanasia is due to cerebral death in conjunction with respiratory arrest and circulatory collapse. Central nervous system depression and hypotension may also occur. Pentobarbital sodium is a short-acting barbiturate used as a sedative, preanesthetic, and sleeping aid. Barbiturates may be habit-forming, and tolerance, psychological, or physical dependence may occur especially following prolonged use of high concentrations. Barbiturates are central nervous system and respiratory depressants. Effects that may be seen following acute exposure include slurred speech, confusion, poor judgement, irritability, insomnia, or incoordination. Effects that may be seen following exposure to high concentrations include severe confusion, decrease or loss of reflexes, severe drowsiness, fever, hypothermia, shortness of breath or troubled breathing, slow heartbeat, severe weakness, respiratory depression, pneumonia, congestive heart failure, renal failure, coma, respiratory arrest, or death. Barbiturates readily cross the placenta following oral administration. Barbiturates have been associated with an increased risk of congenital heart disease, facial abnormalities, and other birth defects; however, no effects have been observed in women exposed to pentobarbital. In addition, newborns that were chronically exposed to bariturates in utero may exhibit withdrawl symptoms such as hyperactivity and tremors. Phenytoin, often administered as phenytoin sodium, is an anticonvulsant and antiarrhythmic agent. Phenytoin is a central nervous system depressant. Acute effects from exposure may include nausea, vomiting, gastrointestinal pain, loss of appetite, dizziness, staggering, blurred vision, nystagmus (involuntary movement of the eye), drowsiness, pupil dilation, hyperactive tendon reflexes, tremor, increased or decreased activity, hallucinations, confusion, respiratory depression, breathing difficulties, or coma. Hypersensitivity reactions, sometimes fatal, have been reported after chronic therapy. General symptoms of potential reactions include fever, general discomfort, rash, facial swelling, skin redness, lymph node effects, hepatitis, anemia, pharyngitis, diarrhea, anorexia, kidney inflammation, and acute inflammation of the lungs. Phenytoin may also invoke autoimmune dysfunction, swelling of the gums, psychological disorders, or effects on the liver or blood. Phenytoin freely pases through the placenta. Human teratogenicity (birth defects) has been reported in women who received phenytoin treatment, and phenytoin has been linked to Fetal Hydantoin Syndrome (FHS). Phenytoin is a teratogen in animals. Propylene glycol is considered to be relatively non-toxic. It is a mild irritant to the eyes and has been reported to irritate the skin. It may cause skin sensitization resulting in allergic contact dermatitis in susceptible individuals. Inhalation exposure to saturated and supersaturated atmospheres of propylene glycol for prolonged periods of time produced no adverse effects. Propylene glycol may cause nervous system depression, acidosis, stupor, and seizures after chronic ingestion. LISTED CARCINOGENS CHEMICAL NAME CAS NUMBER