Trimethoxy(3,3,3-trifluoropropyl)silane

SECTION 2: Hazards identification

CHEMWATCH HAZARD RATINGS Min Max Flammability 2 Toxicity 2 Min/Nil=0 Body Contact 2 Low=1 Reactivity Moderate=2 1 High=3 Chronic 2 Extreme=4 CANADIAN WHMIS SYMBOLS EMERGENCY OVERVIEW RISK Irritating to eyes, respiratory system and skin. Flammable. Harmful to aquatic organisms.

Potential Acute Health Effects

SWALLOWED ■ Accidental ingestion of the material may be damaging to the health of the individual. ■ Methanol may produce a burning or painful sensation in the mouth, throat, chest, and stomach. This may be accompanied by nausea, vomiting, headache, dizziness, shortness of breath, weakness, fatigue, leg cramps, restlessness, confusion, drunken behaviour, visual disturbance, drowsiness, coma and death. EYE ■ This material may produce eye irritation in some persons and produce eye damage 24 hours or more after instillation. Moderate inflammation may be expected with redness; conjunctivitis may occur with prolonged exposure. SKIN ■ The material may cause moderate inflammation of the skin either following direct contact or after a delay of some time. Repeated exposure can cause contact dermatitis which is characterised by redness, swelling and blistering. ■ Skin contact is not thought to have harmful health effects (as classified under EC Directives); the material may still produce health damage following entry through wounds, lesions or abrasions. ■ Open cuts, abraded or irritated skin should not be exposed to this material. ■ Entry into the blood-stream, through, for example, cuts, abrasions or lesions, may produce systemic injury with harmful effects. Examine the skin prior to the use of the material and ensure that any external damage is suitably protected. INHALED ■ The material can cause respiratory irritation in some persons. The body's response to such irritation can cause further lung damage. ■ Inhalation of vapors may cause drowsiness and dizziness. This may be accompanied by sleepiness, reduced alertness, loss of reflexes, lack of co-ordination, and vertigo. ■ Inhalation of vapors or aerosols (mists, fumes), generated by the material during the course of normal handling, may be damaging to the health of the individual. ■ Inhalation hazard is increased at higher temperatures. ■ Minor but regular methanol exposures may effect the central nervous system, optic nerves and retinae. Symptoms may be delayed, with headache, fatigue, nausea, blurring of vision and double vision.

Potential chronic health

■ Long-term exposure to respiratory irritants may result in disease of the airways involving difficult breathing and related systemic problems. Substance accumulation, in the human body, may occur and may cause some concern following repeated or long-term occupational exposure. Long-term exposure to methanol vapor, at concentrations exceeding 3000 ppm, may produce cumulative effects characterised by gastrointestinal disturbances (nausea, vomiting), headache, ringing in the ears, insomnia, trembling, unsteady gait, vertigo, conjunctivitis and clouded or double vision. Liver and/or kidney injury may also result. Some individuals show severe eye damage following prolonged exposure to 800 ppm of the vapor.