Velcade

Sagent Pharmaceuticals

Revision date : 2025-02-06

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GHS08 GHS06
Health risk rating 5
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

69-65-8

Name of the chemical

D-mannitol C6H14O6

Concentration

90.9%

General Information

Version

1.0

Revision date

2025-02-06

Product name

Velcade

Chemical name

[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2- [(pyrazinylcarbonyl) amino]propyl]amino]butyl] boronic acid

1.2.1 Relevant identified uses

Pharmaceutical

Icons in SDS

GHS06 GHS08 M004 M009 M010 M011 M017

Company Information

company name

Sagent Pharmaceuticals

GHS Information

Signal word

Danger

Hazard Codes

Hazard statements (CLP)

H300, H315, H319, H361, H372

Hazard statements

Code

Statements

H300

Fatal if swallowed

Section 2

SECTION 2: Hazards identification

Classification GHS – Classification Acute toxicity (Oral): Category 1 Skin corrosion/irritation: Category 2 Serious eye damage/eye irritation: Category 2A Reproductive toxicity: Category 2 Specific Target Organ Toxicity (repeated exposure):Category Chronic aquatic toxicity: Category 1

Signal word

Danger

Hazard statements

Symbol(s), and/or H300 - Fatal if swallowed. H315 - Causes skin irritation.

Precautionary statements

H319 - Causes serious eye irritation. H361 - Suspected of damaging fertility or the unborn child. H372 - Causes damage to organs through prolonged or repeated exposure.

Prevention

P201- Obtain special instructions before use. P202- Do not handle until all safety precautions have been read and understood. P264- Wash skin thoroughly after handling. P270- Do not eat, drink or smoke when using this product. P280- Wear protective gloves/ eye protection/ face protection. P260- Do not breathe dust. P281- Use personal protective equipment as required.

Response

P301 + P310- IF SWALLOWED: Immediately call a POISON CENTER/doctor. P305 + P351 + P338- IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310- Immediately call a POISON CENTER/doctor. P321- Specific treatment (see supplemental first aid instructions on this label). P330- Rinse mouth.

Disposal

P501: Dispose of contents/ container in accordance with all local and national regulations.

Hazard pictograms

(c) Description of Hazards: N/A (d) Unknown Acute Toxicity: N/A

2.1 Classification of the substance or mixture

GHS – Classification: Acute toxicity (Oral): Category 1 Skin corrosion/irritation: Category 2 Serious eye damage/eye irritation: Category 2A Reproductive toxicity: Category 2 Specific Target Organ Toxicity (repeated exposure):Category 2 Chronic aquatic toxicity: Category 1 (b) Signal Word,

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