Note: Ingredients listed on restricted chemical lists
EC/CAS
7732-18-5
Name of the chemical
Water, distilled, conductivity or of similar purity H2O
Concentration
99.5%
General Information
Version
5.0
Revision date
2021-08-20
Product name
Eloxatin , Eloxatine, Dacplat, Oxaliplatin
Chemical name
cis-[(1 R,2 R)-1,2-cyclohexanediamine-N,N"] [oxalato(2-)- O,O"] platinum
1.2.1 Relevant identified uses
Used in combination with leucovorin for advanced colorectal cancer and adjuvant treatment of stage III colon cancer in patients who have undergone complete resection of the primary tumor
Icons in SDS
Company Information
company name
Sagent Pharmaceuticals, Inc
GHS Information
Signal word
Oxaliplatin injection is an antineoplastic agent and is
Section 2
SECTION 2: Hazards identification
2.1 Classification of the substance or mixture
Mutagenic, cytotoxic, neurotoxic and fetotoxic. The drug substance is a possible carcinogen and a severe eye irritant.
Signal word
Oxaliplatin injection is an antineoplastic agent and is
Hazard statements
considered a Hazardous Drug according to the NIOSH alert: Symbol(s), and/or Preventing Occupational Exposures to Antineoplastic and Other Hazardous Drugs in Health Care Settings. Health care
Precautionary statements
workers who prepare or administer hazardous drugs or who work in areas where these drugs are used should follow specific handling guidelines in order to prevent exposure to these agents in the air or on work surfaces, clothing, medical equipment, or patient urine or feces. See Section 8 for specific handling guidance from the NIOSH Alert for use in the health care setting. (c) Description of Hazards Anticipated signs of overexposure include nausea, vomiting, diarrhea, peripheral neurotoxicity (with cold sensitivity and rare laryngeal dysesthesias, sensation of difficulty with breathing or swallowing), and possible myelosuppression (low blood counts). Mucositis (sore mouth, or soreness of other mucous membranes) and transient elevation of liver enzymes have been observed. As with other platinum compounds allergic reactions have been observed. In therapeutic use, very rare anaphylactoid reactions (severe, possibly life-threatening allergic reactions) have been observed. (d) Unknown Acute Toxicity: N/A
